Peering into the dendritic machinery of striatal medium spiny neurons

D. James Surmeier*, Nelson Spruston

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations


Striatal medium spiny neurons are principal players in the basal ganglia macrocircuits implicated in an astonishing array of psychomotor disorders, including Parkinson's disease, schizophrenia, Huntington's disease, and drug abuse. Using an elegant combination of 2-photon laser scanning microscopy and 2-photon uncaging of glutamate, Carter and Sabatini (this issue of Neuron) provide our first glimpse into the dendrites and spines of striatal medium spiny neurons. The results offer new insights into the workings of these clinically important yet mysterious neurons.

Original languageEnglish (US)
Pages (from-to)401-402
Number of pages2
Issue number3
StatePublished - Oct 28 2004

ASJC Scopus subject areas

  • Neuroscience(all)


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