TY - JOUR
T1 - Penicillin Phenoxymethyl
T2 - Use in Rheumatic Fever Prophylaxis
AU - Phair, John P.
AU - Carleton, Judith
AU - Weihl, Carl
PY - 1973/7
Y1 - 1973/7
N2 - The oral use of penicillin phenoxymethyl in a rheumatic fever prophylaxis program was investigated. The frequency of recurrences of rheumatic fever were low overall (1.6/100 patient years). Among children who complied with the program, as determined by assay of urine for penicillin activity, no recurrences were noted. Approximately three fifths of the children receiving penicillin carried penicillin resistant α-hemolytic streptococci in the oropharynx; resistant organisms were recovered from 22% of control children. The resistant streptococci remained sensitive to erythromycin, lincomycin, and the cephalosporin antibiotics.
AB - The oral use of penicillin phenoxymethyl in a rheumatic fever prophylaxis program was investigated. The frequency of recurrences of rheumatic fever were low overall (1.6/100 patient years). Among children who complied with the program, as determined by assay of urine for penicillin activity, no recurrences were noted. Approximately three fifths of the children receiving penicillin carried penicillin resistant α-hemolytic streptococci in the oropharynx; resistant organisms were recovered from 22% of control children. The resistant streptococci remained sensitive to erythromycin, lincomycin, and the cephalosporin antibiotics.
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U2 - 10.1001/archpedi.1973.02110190044008
DO - 10.1001/archpedi.1973.02110190044008
M3 - Article
C2 - 4198746
AN - SCOPUS:0015828441
SN - 0096-8994
VL - 126
SP - 48
EP - 50
JO - American Journal of Diseases of Children
JF - American Journal of Diseases of Children
IS - 1
ER -