Per-6-bromo-per-2,3-dimethyl-β-cyclodextrin

David Alker; Peter R. Ashton; Valerie D. Harding; Rainer Königer; J. Fraser Stoddart; Andrew J P White; David J. Williams

doi:10.1016/0040-4039(94)88436-6

Per-6-bromo-per-2,3-dimethyl-β-cyclodextrin

David Alker^*, Peter R. Ashton, Valerie D. Harding, Rainer Königer, J. Fraser Stoddart, Andrew J P White, David J. Williams

^*Corresponding author for this work

Chemistry

Research output: Contribution to journal › Article › peer-review

14 Scopus citations

Abstract

An efficient synthesis of the title compound, per-6-bromo-per-2,3-dimethylβ-cyclodextrin, is described, giving access to a highly soluble cyclodextrin, which may be used for further chemical modification of β-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, revealing a cyclodextrin derivative whose conformation deviates substantially from C₇ symmetry.

Original language	English (US)
Pages (from-to)	9091-9094
Number of pages	4
Journal	Tetrahedron Letters
Volume	35
Issue number	48
DOIs	https://doi.org/10.1016/0040-4039(94)88436-6
State	Published - Nov 28 1994

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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title = "Per-6-bromo-per-2,3-dimethyl-β-cyclodextrin",

abstract = "An efficient synthesis of the title compound, per-6-bromo-per-2,3-dimethylβ-cyclodextrin, is described, giving access to a highly soluble cyclodextrin, which may be used for further chemical modification of β-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, revealing a cyclodextrin derivative whose conformation deviates substantially from C7 symmetry.",

author = "David Alker and Ashton, {Peter R.} and Harding, {Valerie D.} and Rainer K{\"o}niger and Stoddart, {J. Fraser} and White, {Andrew J P} and Williams, {David J.}",

year = "1994",

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doi = "10.1016/0040-4039(94)88436-6",

language = "English (US)",

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pages = "9091--9094",

journal = "Tetrahedron Letters",

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TY - JOUR

T1 - Per-6-bromo-per-2,3-dimethyl-β-cyclodextrin

AU - Alker, David

AU - Ashton, Peter R.

AU - Harding, Valerie D.

AU - Königer, Rainer

AU - Stoddart, J. Fraser

AU - White, Andrew J P

AU - Williams, David J.

PY - 1994/11/28

Y1 - 1994/11/28

N2 - An efficient synthesis of the title compound, per-6-bromo-per-2,3-dimethylβ-cyclodextrin, is described, giving access to a highly soluble cyclodextrin, which may be used for further chemical modification of β-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, revealing a cyclodextrin derivative whose conformation deviates substantially from C7 symmetry.

AB - An efficient synthesis of the title compound, per-6-bromo-per-2,3-dimethylβ-cyclodextrin, is described, giving access to a highly soluble cyclodextrin, which may be used for further chemical modification of β-cyclodextrin. Crystals of the target compound were grown and the solid state structure was determined by X-ray crystallography, revealing a cyclodextrin derivative whose conformation deviates substantially from C7 symmetry.

UR - http://www.scopus.com/inward/record.url?scp=0027946308&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0027946308&partnerID=8YFLogxK

U2 - 10.1016/0040-4039(94)88436-6

DO - 10.1016/0040-4039(94)88436-6

M3 - Article

AN - SCOPUS:0027946308

SN - 0040-4039

VL - 35

SP - 9091

EP - 9094

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 48

ER -

Per-6-bromo-per-2,3-dimethyl-β-cyclodextrin

Abstract

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