Perceptions of partial gland ablation for prostate cancer among men on active surveillance: A qualitative study

Sonia Hur, Michael Tzeng, Eliza Cricco-Lizza, Spyridon Basourakos, Miko Yu, Jessica Ancker, Erika Abramson, Christopher Saigal, Ashley Ross, Jim Hu*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives Partial gland ablation (PGA) therapy is an emerging treatment modality that targets specific areas of biopsy-proven prostate cancer (PCa) to minimize treatment-related morbidity by sparing benign prostate. This qualitative study aims to explore and characterize perceptions and attitudes toward PGA in men with very-low-risk, low-risk, and favorable intermediate-risk PCa on active surveillance (AS). Design 92 men diagnosed with very-low-risk, low-risk, and favorable intermediate-risk PCa on AS were invited to participate in semistructured telephone interviews on PGA. Setting Single tertiary care center located in New York City. Participants 20 men with very-low-risk, low-risk, and favorable intermediate-risk PCa on AS participated in the interviews. Main outcome measures Emerging themes on perceptions and attitudes toward PGA were developed from transcripts inductively coded and analyzed under standardized methodology. Results Four themes were derived from 20 interviews that represent the primary considerations in treatment decision-making: (1) the feeling of psychological safety associated with low-risk disease; (2) preference for minimally invasive treatments; (3) the central role of the physician; (4) and the pursuit of treatment options that align with disease severity. Eleven men (55%) expressed interest in pursuing PGA only if their cancer were to progress, while nine men (45%) expressed interest at the current moment. Conclusions Although an emerging treatment modality, patients were broadly accepting of PGA for PCa, with men primarily debating the risks versus benefits of proactively treating low-risk disease. Additional research on men's preferences and attitudes toward PGA will further guide counseling and shared decision-making for PGA.

Original languageEnglish (US)
Article numbere000068
JournalBMJ Surgery, Interventions, and Health Technologies
Volume3
Issue number1
DOIs
StatePublished - Apr 21 2021

Keywords

  • access
  • active surveillance
  • and evaluation
  • health care quality
  • minimally invasive surgical procedures
  • prostate ablation devices
  • urology devices

ASJC Scopus subject areas

  • Surgery
  • Biomedical Engineering

Fingerprint

Dive into the research topics of 'Perceptions of partial gland ablation for prostate cancer among men on active surveillance: A qualitative study'. Together they form a unique fingerprint.

Cite this