Performance of a Molecular Test for Group A Streptococcus Pharyngitis

Robert R. Tanz, Lauren E. Heaberlin, Erin Harvey, Yiannis L. Katsogridakis, Rebecca Ruhana Burns, Jason Rippe, Stanford T. Shulman

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

We performed a prospective study to determine if the pretest probability of a positive loop-mediated isothermal amplification test is greater when there are more signs and symptoms of GAS pharyngitis. Patients were enrolled if a clinician obtained a GAS RADT. The McIsaac score was calculated. The prevalence of positive LAMP and RADT results increased as the McIsaac score increased. The calculated sensitivity of LAMP was superior to RADT.

Original languageEnglish (US)
Pages (from-to)56-59
Number of pages4
JournalJournal of the Pediatric Infectious Diseases Society
Volume12
Issue number1
DOIs
StatePublished - Feb 9 2023

Keywords

  • Group A streptococcus
  • diagnostic stewardship
  • molecular test
  • nucleic acid amplification test
  • pharyngitis

ASJC Scopus subject areas

  • General Medicine

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