TY - JOUR
T1 - Performance of a Molecular Test for Group A Streptococcus Pharyngitis
AU - Tanz, Robert R.
AU - Heaberlin, Lauren E.
AU - Harvey, Erin
AU - Katsogridakis, Yiannis L.
AU - Burns, Rebecca Ruhana
AU - Rippe, Jason
AU - Shulman, Stanford T.
N1 - Publisher Copyright:
© The Author(s) 2022. Published by Oxford University Press on behalf of The Journal of the Pediatric Infectious Diseases Society. All rights reserved. For permissions, please e-mail: [email protected].
PY - 2023/2/9
Y1 - 2023/2/9
N2 - We performed a prospective study to determine if the pretest probability of a positive loop-mediated isothermal amplification test is greater when there are more signs and symptoms of GAS pharyngitis. Patients were enrolled if a clinician obtained a GAS RADT. The McIsaac score was calculated. The prevalence of positive LAMP and RADT results increased as the McIsaac score increased. The calculated sensitivity of LAMP was superior to RADT.
AB - We performed a prospective study to determine if the pretest probability of a positive loop-mediated isothermal amplification test is greater when there are more signs and symptoms of GAS pharyngitis. Patients were enrolled if a clinician obtained a GAS RADT. The McIsaac score was calculated. The prevalence of positive LAMP and RADT results increased as the McIsaac score increased. The calculated sensitivity of LAMP was superior to RADT.
KW - Group A streptococcus
KW - diagnostic stewardship
KW - molecular test
KW - nucleic acid amplification test
KW - pharyngitis
UR - http://www.scopus.com/inward/record.url?scp=85147782900&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=85147782900&partnerID=8YFLogxK
U2 - 10.1093/jpids/piac115
DO - 10.1093/jpids/piac115
M3 - Article
C2 - 36322677
AN - SCOPUS:85147782900
SN - 2048-7207
VL - 12
SP - 56
EP - 59
JO - Journal of the Pediatric Infectious Diseases Society
JF - Journal of the Pediatric Infectious Diseases Society
IS - 1
ER -