Daniel C. Lee*

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter


Myocardial perfusion is an important measurement in the diagnosis and management of coronary artery disease. While clinical measurement of myocardial perfusion has long been dominated by nuclear imaging, MRI has recently emerged as an alternative method with many significant advantages.Compared to single photon emission computed tomography (SPECT), MRI has much higher resolution, requires no radiation dose, and has the potential for more quantitative measurements. MR perfusion measurement can be complex, however, and when designing an MR perfusion experiment there are a variety of choices to consider. Unfortunately, there is no consensus MRI perfusion implementation that is best for all situations, and choosing the ideal parameters for a given scan requires a careful understanding of the pros and cons of each component of an MRI perfusion experiment. In this chapter, we discuss the different components of cardiac perfusion MRI including pulse sequences, image readout, acceleration techniques, and image analysis. In each section, we review the basic theory behind each technique and then discuss their relative advantages and disadvantages. We conclude with a brief discussion of emerging techniques that are currently being researched.

Original languageEnglish (US)
Title of host publicationBasic Principles of Cardiovascular MRI
Subtitle of host publicationPhysics and Imaging Technique
PublisherSpringer International Publishing
Number of pages14
ISBN (Electronic)9783319221410
ISBN (Print)9783319221403
StatePublished - Jan 1 2015


  • Blood flow
  • CMR
  • MRI
  • Perfusion
  • Pulse sequences

ASJC Scopus subject areas

  • General Medicine


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