Peripheral Neuropathy Research Registry: A prospective cohort

PNRR Study Group

Research output: Contribution to journalArticle

Abstract

The Peripheral Neuropathy Research Registry (PNRR) is a prospective cohort of peripheral neuropathy (PN) patients focused on idiopathic axonal peripheral neuropathy. Patients with diabetic, human immunodeficiency virus-, and chemotherapy-induced peripheral neuropathies are enrolled as comparison groups. The PNRR is a multi-center collaboration initiated and funded by the Foundation for Peripheral Neuropathy (FPN) with the objective to recruit a well characterized cohort of patients with different phenotypes and symptoms in each diagnostic category, and to advance research through development of biomarkers and identification of previously unknown causes of PN. The overall goal of the initiative is to find disease-altering treatments and better symptom relief for patients. We present the study design, types of data collected, and characteristics of the first 1150 patients enrolled. We also discuss ongoing analyses on this dataset, including untargeted-omics methodologies.

Original languageEnglish (US)
Pages (from-to)39-47
Number of pages9
JournalJournal of the Peripheral Nervous System
Volume24
Issue number1
DOIs
StatePublished - Mar 1 2019

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Peripheral Nervous System Diseases
Registries
Research
Biomarkers
HIV
Phenotype
Drug Therapy

ASJC Scopus subject areas

  • Neuroscience(all)
  • Clinical Neurology

Cite this

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title = "Peripheral Neuropathy Research Registry: A prospective cohort",
abstract = "The Peripheral Neuropathy Research Registry (PNRR) is a prospective cohort of peripheral neuropathy (PN) patients focused on idiopathic axonal peripheral neuropathy. Patients with diabetic, human immunodeficiency virus-, and chemotherapy-induced peripheral neuropathies are enrolled as comparison groups. The PNRR is a multi-center collaboration initiated and funded by the Foundation for Peripheral Neuropathy (FPN) with the objective to recruit a well characterized cohort of patients with different phenotypes and symptoms in each diagnostic category, and to advance research through development of biomarkers and identification of previously unknown causes of PN. The overall goal of the initiative is to find disease-altering treatments and better symptom relief for patients. We present the study design, types of data collected, and characteristics of the first 1150 patients enrolled. We also discuss ongoing analyses on this dataset, including untargeted-omics methodologies.",
author = "{PNRR Study Group} and Simone Thomas and Senda Ajroud-Driss and Dimachkie, {Mazen M.} and Christopher Gibbons and Roy Freeman and Simpson, {David M.} and Singleton, {J. Robinson} and Smith, {A. Gordon} and Ahmet H{\"o}ke",
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}

Peripheral Neuropathy Research Registry : A prospective cohort. / PNRR Study Group.

In: Journal of the Peripheral Nervous System, Vol. 24, No. 1, 01.03.2019, p. 39-47.

Research output: Contribution to journalArticle

TY - JOUR

T1 - Peripheral Neuropathy Research Registry

T2 - A prospective cohort

AU - PNRR Study Group

AU - Thomas, Simone

AU - Ajroud-Driss, Senda

AU - Dimachkie, Mazen M.

AU - Gibbons, Christopher

AU - Freeman, Roy

AU - Simpson, David M.

AU - Singleton, J. Robinson

AU - Smith, A. Gordon

AU - Höke, Ahmet

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