Peripheral retinal microaneurysms in chronic leukemia

Lee M. Jampol; Morton F. Goldberg; Bruce Busse

doi:10.1016/0002-9394(75)90139-7

Peripheral retinal microaneurysms in chronic leukemia

Lee M. Jampol^*, Morton F. Goldberg, Bruce Busse

^*Corresponding author for this work

Ophthalmology

Research output: Contribution to journal › Article › peer-review

42 Scopus citations

Abstract

Of 25 patients with chronic leukemia, there was clinical evidence of peripheral retinal microaneurysm formation in two of eight patients with chronic lymphocytic leukemia and six of 17 patients with chronic myelogenous leukemia. There was no proliferative retinopathy in any of the 25 patients. An elevated leukocyte count seemed necessary for microaneurysm formation in leukemia, although some patients with elevated counts had no microaneurysms. The prolonged leukocytosis of chronic leukemia can produce peripheral capillary dropout, vascular stagnation, microaneurysm formation, and, rarely, peripheral proliferative retinopathy similar to sickle cell disease.

Original language	English (US)
Pages (from-to)	242-248
Number of pages	7
Journal	American journal of ophthalmology
Volume	80
Issue number	2
DOIs	https://doi.org/10.1016/0002-9394(75)90139-7
State	Published - Aug 1975

Funding

From the University of Illinois Eye and Ear Infirmary, Chicago, Illinois. This study was supported in part by Postdoctoral Fellowship 1-F22-HL00812-01 from the National Institutes of Health.

ASJC Scopus subject areas

Ophthalmology

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title = "Peripheral retinal microaneurysms in chronic leukemia",

abstract = "Of 25 patients with chronic leukemia, there was clinical evidence of peripheral retinal microaneurysm formation in two of eight patients with chronic lymphocytic leukemia and six of 17 patients with chronic myelogenous leukemia. There was no proliferative retinopathy in any of the 25 patients. An elevated leukocyte count seemed necessary for microaneurysm formation in leukemia, although some patients with elevated counts had no microaneurysms. The prolonged leukocytosis of chronic leukemia can produce peripheral capillary dropout, vascular stagnation, microaneurysm formation, and, rarely, peripheral proliferative retinopathy similar to sickle cell disease.",

author = "Jampol, {Lee M.} and Goldberg, {Morton F.} and Bruce Busse",

note = "Funding Information: From the University of Illinois Eye and Ear Infirmary, Chicago, Illinois. This study was supported in part by Postdoctoral Fellowship 1-F22-HL00812-01 from the National Institutes of Health.",

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AU - Goldberg, Morton F.

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N2 - Of 25 patients with chronic leukemia, there was clinical evidence of peripheral retinal microaneurysm formation in two of eight patients with chronic lymphocytic leukemia and six of 17 patients with chronic myelogenous leukemia. There was no proliferative retinopathy in any of the 25 patients. An elevated leukocyte count seemed necessary for microaneurysm formation in leukemia, although some patients with elevated counts had no microaneurysms. The prolonged leukocytosis of chronic leukemia can produce peripheral capillary dropout, vascular stagnation, microaneurysm formation, and, rarely, peripheral proliferative retinopathy similar to sickle cell disease.

AB - Of 25 patients with chronic leukemia, there was clinical evidence of peripheral retinal microaneurysm formation in two of eight patients with chronic lymphocytic leukemia and six of 17 patients with chronic myelogenous leukemia. There was no proliferative retinopathy in any of the 25 patients. An elevated leukocyte count seemed necessary for microaneurysm formation in leukemia, although some patients with elevated counts had no microaneurysms. The prolonged leukocytosis of chronic leukemia can produce peripheral capillary dropout, vascular stagnation, microaneurysm formation, and, rarely, peripheral proliferative retinopathy similar to sickle cell disease.

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Peripheral retinal microaneurysms in chronic leukemia

Abstract

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ASJC Scopus subject areas

UN SDGs

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