Peripheral retinal microaneurysms in chronic leukemia

Lee M. Jampol*, Morton F. Goldberg, Bruce Busse

*Corresponding author for this work

Research output: Contribution to journalArticle

29 Scopus citations

Abstract

Of 25 patients with chronic leukemia, there was clinical evidence of peripheral retinal microaneurysm formation in two of eight patients with chronic lymphocytic leukemia and six of 17 patients with chronic myelogenous leukemia. There was no proliferative retinopathy in any of the 25 patients. An elevated leukocyte count seemed necessary for microaneurysm formation in leukemia, although some patients with elevated counts had no microaneurysms. The prolonged leukocytosis of chronic leukemia can produce peripheral capillary dropout, vascular stagnation, microaneurysm formation, and, rarely, peripheral proliferative retinopathy similar to sickle cell disease.

Original languageEnglish (US)
Pages (from-to)242-248
Number of pages7
JournalAmerican journal of ophthalmology
Volume80
Issue number2
DOIs
StatePublished - Aug 1975

ASJC Scopus subject areas

  • Ophthalmology

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