Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia

Kelly K. Park; Bailey Tayebi; Lily Uihlein; Jodi Speiser; Adnan Mir; Pedram Gerami; Anthony Mancini; Wendy Kim

doi:10.1111/pde.13366

Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia

Kelly K. Park, Bailey Tayebi, Lily Uihlein, Jodi Speiser, Adnan Mir, Pedram Gerami, Anthony Mancini, Wendy Kim^*

^*Corresponding author for this work

Research output: Contribution to journal › Article › peer-review

4 Scopus citations

Abstract

A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.

Original language	English (US)
Pages (from-to)	e74-e75
Journal	Pediatric dermatology
Volume	35
Issue number	1
DOIs	https://doi.org/10.1111/pde.13366
State	Published - Jan 1 2018

Keywords

acute lymphoblastic leukemia
chilblains
leukemia cutis
pernio

ASJC Scopus subject areas

Dermatology
Pediatrics, Perinatology, and Child Health

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10.1111/pde.13366

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title = "Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia",

abstract = "A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.",

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AU - Park, Kelly K.

AU - Tayebi, Bailey

AU - Uihlein, Lily

AU - Speiser, Jodi

AU - Mir, Adnan

AU - Gerami, Pedram

AU - Mancini, Anthony

AU - Kim, Wendy

PY - 2018/1/1

Y1 - 2018/1/1

N2 - A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.

AB - A previously healthy 5-year-old girl presented with acute onset of blue toes and red spots on the nose and fingers. The striking nature of these lesions, along with the finding of submandibular lymphadenopathy, prompted further evaluation. Laboratory findings were remarkable for anemia, high transaminase levels, and high blast count. Histopathologic findings were consistent with early pernio. Further examination revealed acute B-cell lymphoblastic leukemia. Treatment of the leukemia led to resolution of the pernio.

KW - acute lymphoblastic leukemia

KW - chilblains

KW - leukemia cutis

KW - pernio

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ER -

Pernio as the presenting sign of blast crisis in acute lymphoblastic leukemia

Abstract

Keywords

ASJC Scopus subject areas

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