Persistent pupillary dilation in herpes simplex uveitis

Debra A. Goldstein, Andrew A. Mis, Frederick S. Oh, Jean G. Deschenes

Research output: Contribution to journalArticlepeer-review

11 Scopus citations


Objective: To report the association between herpes simplex virus (HSV) and iris atrophy with pupillary dilation. Design: Retrospective case series. Participants: Patients with a clinical diagnosis of HSV keratouveitis seen between November 1993 and April 1994 in a single university uveitis clinic. There were 6 women and 7 men, aged 17 to 69 years (mean age 44.4 years). Methods: Patient information was collected, including history and medications used, and a complete ophthalmologic evaluation was performed, with careful documentation of iris detail and pupillary size. Results: Thirteen of 13 patients demonstrated some degree of iris atrophy; 9 of 13 had pupillary dilation on the affected side despite not being on dilating drops. Conclusions: Iris atrophy and pupillary dilation in a patient with unexplained anterior uveitis suggests the diagnosis of HSV keratouveitis.

Original languageEnglish (US)
Pages (from-to)314-316
Number of pages3
JournalCanadian Journal of Ophthalmology
Issue number3
StatePublished - Jun 2009


  • Dilation
  • Herpes simplex
  • Iridocyclitis
  • Iris atrophy
  • Mydriasis
  • Pupil
  • Uveitis

ASJC Scopus subject areas

  • Ophthalmology


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