TY - JOUR
T1 - Personality Changes in Alzheimer's Disease
AU - Bózzola, Fernando C.
AU - Gorelick, Philip B.
AU - Freels, Sally
PY - 1992/3
Y1 - 1992/3
N2 - We profiled personality changes that were measured cross-sectionally on the Blessed Dementia Scale in 80 patients with Alzheimer's disease who were examined at a dementia clinic. The most common personality changes were diminished initiative/growing apathy (61.3%), relinquishment of hobbies (55.0%), and increased rigidity (41.3%). The least frequent personality change was sexual misdemeanor (3.8%). Discriminant function analysis showed that the Global Deterioration Scale, the Clinical Rating Scale for Symptoms of Psychosis in Alzheimer's Disease, and the duration of dementia symptoms were the best predictors to classify personality change in an overall score of personality. However, cognitive impairment, as measured by the Blessed Memory-Information-Concentration Test and Mini-Mental State Examination, was not a good predictor of overall personality change. Personality and behavioral changes are common in Alzheimer's disease and may not be attributed entirely to intellectual impairment.
AB - We profiled personality changes that were measured cross-sectionally on the Blessed Dementia Scale in 80 patients with Alzheimer's disease who were examined at a dementia clinic. The most common personality changes were diminished initiative/growing apathy (61.3%), relinquishment of hobbies (55.0%), and increased rigidity (41.3%). The least frequent personality change was sexual misdemeanor (3.8%). Discriminant function analysis showed that the Global Deterioration Scale, the Clinical Rating Scale for Symptoms of Psychosis in Alzheimer's Disease, and the duration of dementia symptoms were the best predictors to classify personality change in an overall score of personality. However, cognitive impairment, as measured by the Blessed Memory-Information-Concentration Test and Mini-Mental State Examination, was not a good predictor of overall personality change. Personality and behavioral changes are common in Alzheimer's disease and may not be attributed entirely to intellectual impairment.
UR - http://www.scopus.com/inward/record.url?scp=0026609058&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0026609058&partnerID=8YFLogxK
U2 - 10.1001/archneur.1992.00530270117027
DO - 10.1001/archneur.1992.00530270117027
M3 - Article
C2 - 1536633
AN - SCOPUS:0026609058
VL - 49
SP - 297
EP - 300
JO - Archives of Neurology
JF - Archives of Neurology
SN - 0003-9942
IS - 3
ER -