TY - JOUR
T1 - Personalized physical rehabilitation program and employment in kidney transplant recipients
T2 - a randomized trial
AU - Kastelz, Alexandra
AU - Fernhall, Bo
AU - Wang, Edward
AU - Tzvetanov, Ivo
AU - Spaggiari, Mario
AU - Shetty, Aneesha
AU - Gallon, Lorenzo
AU - Hachaj, Greg
AU - Kaplan, Bruce
AU - Benedetti, Enrico
N1 - Funding Information:
The authors have declared no funding.
Publisher Copyright:
© 2021 Steunstichting ESOT. Published by John Wiley & Sons Ltd
PY - 2021/6
Y1 - 2021/6
N2 - Kidney transplantation is the preferred treatment for kidney failure; however after transplant, reduced physical function, poor self-perceptions, and unemployment are common concerns that remain. This randomized controlled trial compared the effects of a 12-month exercise rehabilitation program (intervention) to standard care alone (control) in kidney transplant recipients. The exercise intervention consisted of a 2 day/week, 60-minute personalized, one-on-one, resistance-based exercise trainings. Eighty participants completed the study (52 intervention vs. 28 control). For individuals unemployed at baseline, there was a 52.3% increase in employment compared to 13.3 % increase in the control group after 12 months (P = <0.0001). For those already employed at baseline, 100% of individuals maintained employment in both groups after 12 months (P = 0.4742). For all comers, there was a positive trend for Global Physical Health (P = 0.0034), Global Mental Health (P = 0.0064), and Physical Function (P = 0.0075), with the intervention group showing greater improvements. These findings suggest the implementation of an exercise rehabilitation program postkidney transplant can be beneficial to increase employment for individuals previously unemployed, improve self-perceived health, physical function, and mental health, overall contributing to better health outcomes in kidney transplant recipients. (Clinicaltrials.gov number: NCT02409901).
AB - Kidney transplantation is the preferred treatment for kidney failure; however after transplant, reduced physical function, poor self-perceptions, and unemployment are common concerns that remain. This randomized controlled trial compared the effects of a 12-month exercise rehabilitation program (intervention) to standard care alone (control) in kidney transplant recipients. The exercise intervention consisted of a 2 day/week, 60-minute personalized, one-on-one, resistance-based exercise trainings. Eighty participants completed the study (52 intervention vs. 28 control). For individuals unemployed at baseline, there was a 52.3% increase in employment compared to 13.3 % increase in the control group after 12 months (P = <0.0001). For those already employed at baseline, 100% of individuals maintained employment in both groups after 12 months (P = 0.4742). For all comers, there was a positive trend for Global Physical Health (P = 0.0034), Global Mental Health (P = 0.0064), and Physical Function (P = 0.0075), with the intervention group showing greater improvements. These findings suggest the implementation of an exercise rehabilitation program postkidney transplant can be beneficial to increase employment for individuals previously unemployed, improve self-perceived health, physical function, and mental health, overall contributing to better health outcomes in kidney transplant recipients. (Clinicaltrials.gov number: NCT02409901).
KW - employment
KW - exercise
KW - kidney transplant
KW - physical rehabilitation
KW - quality of life
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U2 - 10.1111/tri.13868
DO - 10.1111/tri.13868
M3 - Article
C2 - 33733479
AN - SCOPUS:85104117483
VL - 34
SP - 1083
EP - 1092
JO - Transplant International
JF - Transplant International
SN - 0934-0874
IS - 6
ER -