Pertussus is rare in human immunodeficiency virus disease

S. E. Cohn*, K. L. Knorr, P. H. Gilligan, M. L. Smiley, D. J. Weber

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

20 Scopus citations


Many adults are susceptible to pertussis, and Bordetella pertussis has been isolated from five patients with HIV disease. The prevalence of B. pertussis in 60 HIV-infected adults with nasopharyngeal (NP) swab cultures were studied and questionnaires were used that assessed HIV-related risk behaviors and disease status, immunization history, and symptoms of respiratory disease. Although 72% had cough and 33% had cough for > 14 days, no nasopharyngeal (NP) swab cultures were positive for Bordetella species. Of the 44 (73%) patients who had follow-up NP swab cultures at 6 months, all were still negative. On the basis of these data from our HIV-infected population, the estimated population prevalence of pertussis is zero, with an upper 95% confidence limit of 0.00065, or fewer than 6.5 cases of pertussis per 10,000 HIV-infected adults. Given this low prevalence, HIV-infected patients with respiratory symptoms do not appear to be a reservoir for B. pertussis in the community.

Original languageEnglish (US)
Pages (from-to)411-413
Number of pages3
JournalAmerican Review of Respiratory Disease
Issue number2
StatePublished - 1993

ASJC Scopus subject areas

  • Pulmonary and Respiratory Medicine


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