PET imaging of maze processing

Stephen Flitman*, Joy O'Grady, Valerie Cooper, Jordan Grafman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


Covered maze traversal models nonverbal planning, involving sequential execution of moves using learned spatial maps. To determine the neural substrate involved in maze processing, eleven adults underwent [H215O]-PET while performing motor control, following the computer; visual control, choosing the wall with more dead-ends; uncovered maze, traversing fully visible mazes; covered maze, traversing mazes only locally visible. Maze processing lateralizes to the right hemisphere: uncovered maze versus controls revealed area 23 and 29 activation; covered maze versus controls activated areas 8, 10 and 19. The extrastriate region may store path information, evoked by prefrontal areas for spatial planning and navigation.

Original languageEnglish (US)
Pages (from-to)409-420
Number of pages12
Issue number4
StatePublished - Feb 28 1997


  • Functional neuroimaging
  • Maze learning
  • PET
  • Spatial processing

ASJC Scopus subject areas

  • Experimental and Cognitive Psychology
  • Cognitive Neuroscience
  • Behavioral Neuroscience


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