Pharmacodynamics of inhalation agents

Carly C. Guthrie, Jeffrey Lu

Research output: Chapter in Book/Report/Conference proceedingChapter


Minimum alveolar concentration (MAC): one MAC is the level of inhaled anesthetic, reflected in the end-tidal anesthetic gas, which prevents movement to surgical stimulus in 50% of patients. MAC values are additive, meaning that 0.5 MAC of nitrous oxide and 0.5 MAC of sevoflurane will provide 1 MAC of anesthesia. MAC awake, the level of anesthetic at which the patient awakens is approximately 0.3 MAC. MAC decreases by 6% per decade of age.

Original languageEnglish (US)
Title of host publicationEssential Clinical Anesthesia Review
Subtitle of host publicationKeywords, Questions and Answers for the Boards
PublisherCambridge University Press
Number of pages3
ISBN (Electronic)9781139584005
ISBN (Print)9781107681309
StatePublished - Jan 1 2015


  • Bronchomotor tone
  • Cardiac effects of inhalation agents
  • Central nervous system effects
  • Factors that change MAC
  • Halothane and arrhythmias
  • MAC changes with age
  • Metabolism rates
  • Minimum alveolar concentration
  • Neuromuscular blocking agents
  • Pulmonary ventilation and inhalation agents

ASJC Scopus subject areas

  • Medicine(all)

Fingerprint Dive into the research topics of 'Pharmacodynamics of inhalation agents'. Together they form a unique fingerprint.

Cite this