Pharmacodynamics of inhalation agents

Carly C. Guthrie; Jeffrey Lu

doi:10.1017/CBO9781139584005.034

Pharmacodynamics of inhalation agents

Carly C. Guthrie, Jeffrey Lu

Anesthesiology

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

Minimum alveolar concentration (MAC): one MAC is the level of inhaled anesthetic, reflected in the end-tidal anesthetic gas, which prevents movement to surgical stimulus in 50% of patients. MAC values are additive, meaning that 0.5 MAC of nitrous oxide and 0.5 MAC of sevoflurane will provide 1 MAC of anesthesia. MAC awake, the level of anesthetic at which the patient awakens is approximately 0.3 MAC. MAC decreases by 6% per decade of age.

Original language	English (US)
Title of host publication	Essential Clinical Anesthesia Review
Subtitle of host publication	Keywords, Questions and Answers for the Boards
Publisher	Cambridge University Press
Pages	121-123
Number of pages	3
ISBN (Electronic)	9781139584005
ISBN (Print)	9781107681309
DOIs	https://doi.org/10.1017/CBO9781139584005.034
State	Published - Jan 1 2015

Keywords

Bronchomotor tone
Cardiac effects of inhalation agents
Central nervous system effects
Factors that change MAC
Halothane and arrhythmias
MAC changes with age
Metabolism rates
Minimum alveolar concentration
Neuromuscular blocking agents
Pulmonary ventilation and inhalation agents

ASJC Scopus subject areas

General Medicine

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10.1017/CBO9781139584005.034

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abstract = "Minimum alveolar concentration (MAC): one MAC is the level of inhaled anesthetic, reflected in the end-tidal anesthetic gas, which prevents movement to surgical stimulus in 50% of patients. MAC values are additive, meaning that 0.5 MAC of nitrous oxide and 0.5 MAC of sevoflurane will provide 1 MAC of anesthesia. MAC awake, the level of anesthetic at which the patient awakens is approximately 0.3 MAC. MAC decreases by 6% per decade of age.",

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KW - MAC changes with age

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Pharmacodynamics of inhalation agents

Abstract

Keywords

ASJC Scopus subject areas

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