Pharmacodynamics of inhalation agents

Carly C. Guthrie, Jeffrey Lu

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Minimum alveolar concentration (MAC): one MAC is the level of inhaled anesthetic, reflected in the end-tidal anesthetic gas, which prevents movement to surgical stimulus in 50% of patients. MAC values are additive, meaning that 0.5 MAC of nitrous oxide and 0.5 MAC of sevoflurane will provide 1 MAC of anesthesia. MAC awake, the level of anesthetic at which the patient awakens is approximately 0.3 MAC. MAC decreases by 6% per decade of age.

Original languageEnglish (US)
Title of host publicationEssential Clinical Anesthesia Review
Subtitle of host publicationKeywords, Questions and Answers for the Boards
PublisherCambridge University Press
Pages121-123
Number of pages3
ISBN (Electronic)9781139584005
ISBN (Print)9781107681309
DOIs
StatePublished - Jan 1 2015

Keywords

  • Bronchomotor tone
  • Cardiac effects of inhalation agents
  • Central nervous system effects
  • Factors that change MAC
  • Halothane and arrhythmias
  • MAC changes with age
  • Metabolism rates
  • Minimum alveolar concentration
  • Neuromuscular blocking agents
  • Pulmonary ventilation and inhalation agents

ASJC Scopus subject areas

  • Medicine(all)

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