Pharmacotherapy in the critically ill child with acute kidney injury

M. T. Bigham, T. K. Hutson, D. S. Wheeler

Research output: Chapter in Book/Report/Conference proceedingChapter


Core Messages: Several commonly used medications in the pediatric intensive care unit (PICU) are potentially toxic to the kidney. The kidney plays a major role in determining the absorption, distribution, metabolism, and elimination of a multitude of medications that are commonly used in the PICU. As such, dosing of these medications needs to be adjusted in critically ill children with acute kidney injury. Renal replacement therapy can affect the drug levels of commonly used medications in the PICU.

Original languageEnglish (US)
Title of host publicationPediatric Nephrology in the ICU
PublisherSpringer Berlin Heidelberg
Number of pages16
ISBN (Print)9783540744238
StatePublished - Dec 1 2009
Externally publishedYes

ASJC Scopus subject areas

  • Medicine(all)

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