Phase I and pharmacodynamic study of Triapine®, a novel ribonucleotide reductase inhibitor, in patients with advanced leukemia

Francis J. Giles*, Paula M. Fracasso, Hagop M. Kantarjian, Jorge E. Cortes, Randy A. Brown, Srdan Verstovsek, Yesid Alvarado, Deborah A. Thomas, Stefan Faderl, Guillermo Garcia-Manero, Lisa P. Wright, Tom Samson, Ann Cahill, Paula Lambert, William Plunkett, Mario Sznol, John F. DiPersio, Varsha Gandhi

*Corresponding author for this work

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Pharmacology, Toxicology and Pharmaceutical Science