Phenoxyethanol is effective topical therapy of Gram-negative cellulitis in neutropenic patients

P. Mitchell; R. Powles; K. Rege; J. Treleaven; D. Catovsky; J. Mehta; B. Jameson

doi:10.1016/0195-6701(93)90008-N

Phenoxyethanol is effective topical therapy of Gram-negative cellulitis in neutropenic patients

P. Mitchell^*, R. Powles, K. Rege, J. Treleaven, D. Catovsky, J. Mehta, B. Jameson

^*Corresponding author for this work

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Article › peer-review

5 Scopus citations

Abstract

In neutropenic patients cellulitis caused by Gram-negative organisms may prove difficult to control and cause considerable tissue damage. Phenoxyethanol has activity against a range of bacteria, including Pseudomonas aeruginosa, and is absorbed by intact skin. Three severely neutropenic patients are described in whom cellulitis failed to respond to appropriate intravenous antibiotics. However the topical application of phenoxyethanol solution gave prompt local control. This cheap and nontoxic agent may give dramatic improvement in this difficult clinical situation.

Original language	English (US)
Pages (from-to)	53-56
Number of pages	4
Journal	Journal of Hospital Infection
Volume	25
Issue number	1
DOIs	https://doi.org/10.1016/0195-6701(93)90008-N
State	Published - Jan 1 1993

Keywords

Phenoxyethanol
cellulitis
immunocompromised

ASJC Scopus subject areas

Applied Microbiology and Biotechnology
Microbiology
Parasitology
Virology
Immunology and Allergy
Infectious Diseases

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1016/0195-6701(93)90008-N

Cite this

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title = "Phenoxyethanol is effective topical therapy of Gram-negative cellulitis in neutropenic patients",

abstract = "In neutropenic patients cellulitis caused by Gram-negative organisms may prove difficult to control and cause considerable tissue damage. Phenoxyethanol has activity against a range of bacteria, including Pseudomonas aeruginosa, and is absorbed by intact skin. Three severely neutropenic patients are described in whom cellulitis failed to respond to appropriate intravenous antibiotics. However the topical application of phenoxyethanol solution gave prompt local control. This cheap and nontoxic agent may give dramatic improvement in this difficult clinical situation.",

keywords = "Phenoxyethanol, cellulitis, immunocompromised",

author = "P. Mitchell and R. Powles and K. Rege and J. Treleaven and D. Catovsky and J. Mehta and B. Jameson",

year = "1993",

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T1 - Phenoxyethanol is effective topical therapy of Gram-negative cellulitis in neutropenic patients

AU - Mitchell, P.

AU - Powles, R.

AU - Rege, K.

AU - Treleaven, J.

AU - Catovsky, D.

AU - Mehta, J.

AU - Jameson, B.

PY - 1993/1/1

Y1 - 1993/1/1

N2 - In neutropenic patients cellulitis caused by Gram-negative organisms may prove difficult to control and cause considerable tissue damage. Phenoxyethanol has activity against a range of bacteria, including Pseudomonas aeruginosa, and is absorbed by intact skin. Three severely neutropenic patients are described in whom cellulitis failed to respond to appropriate intravenous antibiotics. However the topical application of phenoxyethanol solution gave prompt local control. This cheap and nontoxic agent may give dramatic improvement in this difficult clinical situation.

AB - In neutropenic patients cellulitis caused by Gram-negative organisms may prove difficult to control and cause considerable tissue damage. Phenoxyethanol has activity against a range of bacteria, including Pseudomonas aeruginosa, and is absorbed by intact skin. Three severely neutropenic patients are described in whom cellulitis failed to respond to appropriate intravenous antibiotics. However the topical application of phenoxyethanol solution gave prompt local control. This cheap and nontoxic agent may give dramatic improvement in this difficult clinical situation.

KW - Phenoxyethanol

KW - cellulitis

KW - immunocompromised

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DO - 10.1016/0195-6701(93)90008-N

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AN - SCOPUS:0027508222

SN - 0195-6701

VL - 25

SP - 53

EP - 56

JO - Journal of Hospital Infection

JF - Journal of Hospital Infection

IS - 1

ER -

Phenoxyethanol is effective topical therapy of Gram-negative cellulitis in neutropenic patients

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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