Abstract
Phonological processing deficits are characteristic of both the agrammatic and logopenic subtypes of primary progressive aphasia (PPA-G and PPA-L). However, it is an open question which substages of phonological processing (i.e., phonological word form retrieval, phonological encoding) are impaired in these subtypes of PPA, as well as how phonological processing deficits contribute to anomia. In the present study, participants with PPA-G (n = 7), participants with PPA-L (n = 7), and unimpaired controls (n = 17) named objects as interfering written words (phonologically related/unrelated) were presented at different stimulus onset asynchronies (SOAs) of 0, +100, +300, and +500 ms. Phonological facilitation (PF) effects (faster naming times with phonologically related interfering words) were found for the controls and PPA-L group only at SOA = 0 and +100 ms. However, the PPA-G group exhibited protracted PF effects (PF at SOA = 0, +100, and +300 ms). These results may reflect deficits in phonological encoding in PPA-G, but not in PPA-L, supporting the neuropsychological reality of this substage of phonological processing and the distinction between these two PPA subtypes.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 172-193 |
| Number of pages | 22 |
| Journal | Cognitive Neuropsychology |
| Volume | 30 |
| Issue number | 3 |
| DOIs | |
| State | Published - May 1 2013 |
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Keywords
- Anomia
- Phonological processing
- Picture-word interference paradigm
- Primary progressive aphasia
ASJC Scopus subject areas
- Neuropsychology and Physiological Psychology
- Experimental and Cognitive Psychology
- Developmental and Educational Psychology
- Arts and Humanities (miscellaneous)
- Cognitive Neuroscience
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Phonological facilitation of object naming in agrammatic and logopenic primary progressive aphasia (PPA). / Mack, Jennifer E; Cho-Reyes, Soojin; Kloet, James D.; Weintraub, Sandra; Mesulam, Marek-Marsel; Thompson, Cynthia K.
In: Cognitive Neuropsychology, Vol. 30, No. 3, 01.05.2013, p. 172-193.Research output: Contribution to journal › Article
TY - JOUR
T1 - Phonological facilitation of object naming in agrammatic and logopenic primary progressive aphasia (PPA)
AU - Mack, Jennifer E
AU - Cho-Reyes, Soojin
AU - Kloet, James D.
AU - Weintraub, Sandra
AU - Mesulam, Marek-Marsel
AU - Thompson, Cynthia K
PY - 2013/5/1
Y1 - 2013/5/1
N2 - Phonological processing deficits are characteristic of both the agrammatic and logopenic subtypes of primary progressive aphasia (PPA-G and PPA-L). However, it is an open question which substages of phonological processing (i.e., phonological word form retrieval, phonological encoding) are impaired in these subtypes of PPA, as well as how phonological processing deficits contribute to anomia. In the present study, participants with PPA-G (n = 7), participants with PPA-L (n = 7), and unimpaired controls (n = 17) named objects as interfering written words (phonologically related/unrelated) were presented at different stimulus onset asynchronies (SOAs) of 0, +100, +300, and +500 ms. Phonological facilitation (PF) effects (faster naming times with phonologically related interfering words) were found for the controls and PPA-L group only at SOA = 0 and +100 ms. However, the PPA-G group exhibited protracted PF effects (PF at SOA = 0, +100, and +300 ms). These results may reflect deficits in phonological encoding in PPA-G, but not in PPA-L, supporting the neuropsychological reality of this substage of phonological processing and the distinction between these two PPA subtypes.
AB - Phonological processing deficits are characteristic of both the agrammatic and logopenic subtypes of primary progressive aphasia (PPA-G and PPA-L). However, it is an open question which substages of phonological processing (i.e., phonological word form retrieval, phonological encoding) are impaired in these subtypes of PPA, as well as how phonological processing deficits contribute to anomia. In the present study, participants with PPA-G (n = 7), participants with PPA-L (n = 7), and unimpaired controls (n = 17) named objects as interfering written words (phonologically related/unrelated) were presented at different stimulus onset asynchronies (SOAs) of 0, +100, +300, and +500 ms. Phonological facilitation (PF) effects (faster naming times with phonologically related interfering words) were found for the controls and PPA-L group only at SOA = 0 and +100 ms. However, the PPA-G group exhibited protracted PF effects (PF at SOA = 0, +100, and +300 ms). These results may reflect deficits in phonological encoding in PPA-G, but not in PPA-L, supporting the neuropsychological reality of this substage of phonological processing and the distinction between these two PPA subtypes.
KW - Anomia
KW - Phonological processing
KW - Picture-word interference paradigm
KW - Primary progressive aphasia
UR - http://www.scopus.com/inward/record.url?scp=84885384920&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84885384920&partnerID=8YFLogxK
U2 - 10.1080/02643294.2013.835717
DO - 10.1080/02643294.2013.835717
M3 - Article
C2 - 24070176
AN - SCOPUS:84885384920
VL - 30
SP - 172
EP - 193
JO - Cognitive Neuropsychology
JF - Cognitive Neuropsychology
SN - 0264-3294
IS - 3
ER -