Phospho-specific flow cytometry in drug discovery

Matthew R. Clutter, Peter O. Krutzik, Garry P. Nolan*

*Corresponding author for this work

    Research output: Contribution to journalReview articlepeer-review

    10 Scopus citations


    Here we present phospho-specific flow cytometry as a new tool for drug discovery with applications throughout the drug development pipeline, from target identification to library screening, disease model assessment and clinical screening and diagnostics. The single cell, multiparameter nature of flow cytometry generates high-content datasets, and current improvements in the technology are rapidly increasing its high-throughput capacity, making it a valuable platform in modern drug discovery.

    Original languageEnglish (US)
    Pages (from-to)295-302
    Number of pages8
    JournalDrug Discovery Today: Technologies
    Issue number3
    StatePublished - 2005

    ASJC Scopus subject areas

    • Molecular Medicine
    • Drug Discovery


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