Phospho-specific flow cytometry in drug discovery

Matthew R. Clutter, Peter O. Krutzik, Garry P. Nolan*

*Corresponding author for this work

Research output: Contribution to journalReview article

10 Scopus citations

Abstract

Here we present phospho-specific flow cytometry as a new tool for drug discovery with applications throughout the drug development pipeline, from target identification to library screening, disease model assessment and clinical screening and diagnostics. The single cell, multiparameter nature of flow cytometry generates high-content datasets, and current improvements in the technology are rapidly increasing its high-throughput capacity, making it a valuable platform in modern drug discovery.

Original languageEnglish (US)
Pages (from-to)295-302
Number of pages8
JournalDrug Discovery Today: Technologies
Volume2
Issue number3
DOIs
StatePublished - Jan 1 2005

    Fingerprint

ASJC Scopus subject areas

  • Molecular Medicine
  • Drug Discovery

Cite this