Abstract
The eye relies on the synergistic cooperation of many different ocular components, including the cornea, crystalline lens, photoreceptors, and retinal neurons, to precisely sense visual information. Complications with a single ocular component can degrade vision and sometimes cause blindness. Immediate treatment and long-term monitoring are paramount to alleviate symptoms, restore vision, and cure ocular diseases. However, successful treatment requires understanding ocular pathological mechanisms, precisely detecting and monitoring the diseases. The investigation and diagnosis of ocular diseases require advanced medical tools. In this mini review, we discuss non-invasive photoacoustic (PA) imaging as a potential research tool and medical screening device. In the research setting, PA imaging can provide valuable information on the disease progression. In the clinical setting, PA imaging can potentially aid in disease detection and treatment monitoring.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 112-123 |
| Number of pages | 12 |
| Journal | Photoacoustics |
| Volume | 4 |
| Issue number | 3 |
| DOIs | |
| State | Published - Sep 1 2016 |
Funding
The authors would like to thank Dr. Hao Li and Dr. Biqin Dong for fruitful discussions. This work was supported by NIH grants 1R01EY019951 , 1R24EY022883 , and 1DP3DK108248 ; and NSF grants CBET-1055379 and DBI-1353952 . Wenzhong Liu is supported by the International Graduate Research Fellowship from the Howard Hughes Medical Institute.
Keywords
- Diseases detection
- Eye
- Medical tools
- Photoacoustic imaging
- Treatment monitoring
ASJC Scopus subject areas
- Atomic and Molecular Physics, and Optics
- Radiology Nuclear Medicine and imaging