Abstract
We report three new cases of patients with Sturge-Weber Syndrome and symptomatic retinal detachments from diffuse choroidal hemangiomas successfully treated with photodynamic therapy (PDT) and review medical literature on the available treatment options for choroidal hemangiomas. All patients were treated with a single session of PDT with verteporfin infused at a concentration of 6 mg/m2 and treated for 83 seconds with 689-nm Zeiss laser that was delivered with total energy level of 50 J/cm2 with an intensity of 600 mW/cm2. The exudative retinal detachment (RD) and macular edema completely resolved in all cases by 1-4 months after PDT treatment. Visual acuity improved in all three cases with diminished tumor size in the areas of treatment. One case was followed for 5 months, another for 2 years, and the third case for 6 years, with no recurrence of exudative RD. PDT is an effective treatment option for visual deterioration from exudative retinal detachment in patients with diffuse choroidal hemangiomas.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 68-85 |
| Number of pages | 18 |
| Journal | Survey of ophthalmology |
| Volume | 56 |
| Issue number | 1 |
| DOIs | |
| State | Published - Jan 2011 |
Funding
The authors reported no proprietary or commercial interest in any product mentioned or concept discussed in this article. Publication of this article was supported in part by an unrestricted grant from Research to Prevent Blindness, Inc., New York City, NY.
Keywords
- Age-related macular degeneration
- Circumscribed and diffuse choroidal hemangioma
- Cystoid macular edema
- Laser photocoagulation
- PDT
- Photodynamic therapy
- Preretinal fibrosis
- Proton beam radiotherapy
- Radiation therapy
- Stereotactic radiotherapy
- Transpupillary thermotherapy
- Verteporfin
ASJC Scopus subject areas
- Ophthalmology