Photon radiotherapy for the treatment of high-grade gliomas

Catherine S. Hwang; Maryann H. Marymont; Kenji Muro

doi:10.1586/14737140.7.12.S37

Photon radiotherapy for the treatment of high-grade gliomas

Catherine S. Hwang^*, Maryann H. Marymont, Kenji Muro

^*Corresponding author for this work

Radiation Oncology

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.

Original language	English (US)
Pages (from-to)	S37-S43
Journal	Expert review of anticancer therapy
Volume	7
Issue number	12 SUPPL.
DOIs	https://doi.org/10.1586/14737140.7.12.S37
State	Published - Dec 2007

Keywords

Anaplastic astrocytoma
Brachytherapy
Glioblastoma multiforme
Radiotherapy
Stereotactic

ASJC Scopus subject areas

Oncology
Pharmacology (medical)

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10.1586/14737140.7.12.S37

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title = "Photon radiotherapy for the treatment of high-grade gliomas",

abstract = "High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.",

keywords = "Anaplastic astrocytoma, Brachytherapy, Glioblastoma multiforme, Radiotherapy, Stereotactic",

author = "Hwang, {Catherine S.} and Marymont, {Maryann H.} and Kenji Muro",

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T1 - Photon radiotherapy for the treatment of high-grade gliomas

AU - Hwang, Catherine S.

AU - Marymont, Maryann H.

AU - Muro, Kenji

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N2 - High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.

AB - High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.

KW - Anaplastic astrocytoma

KW - Brachytherapy

KW - Glioblastoma multiforme

KW - Radiotherapy

KW - Stereotactic

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JO - Expert review of anticancer therapy

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Photon radiotherapy for the treatment of high-grade gliomas

Abstract

Keywords

ASJC Scopus subject areas

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