Photon radiotherapy for the treatment of high-grade gliomas

Catherine S. Hwang*, Maryann H. Marymont, Kenji Muro

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

1 Scopus citations

Abstract

High-grade gliomas are diseases characterized by poor overall survival despite aggressive multimodality therapy. Radiation therapy has been unequivocally established as the mainstay of therapy after surgical intervention, regardless of the extent of surgical resection. Despite theoretical and technological advances in the planning and delivery of radiation therapy, overall survival remains grim. In this review, we outline the evolution of radiation therapy, report the pivotal trials that have shaped this therapy and speculate on the future direction of this field.

Original languageEnglish (US)
JournalExpert review of anticancer therapy
Volume7
Issue number12 SUPPL.
DOIs
StatePublished - Dec 1 2007

Keywords

  • Anaplastic astrocytoma
  • Brachytherapy
  • Glioblastoma multiforme
  • Radiotherapy
  • Stereotactic

ASJC Scopus subject areas

  • Oncology
  • Pharmacology (medical)

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