Abstract
Receptor inactivation by means of chromophore-conjugated receptor ligands and lasers is discussed. The results of preliminary experiments aimed at inactivation of FMRFamide receptors in snail neurons using a He-Ne laser and FMRFamide analogs conjugated with Azure B are presented. Because the conjugates synthesized apparently bound to another class of binding sites on the neuronal membrane, the FMRFamide receptor inactivation was not achieved. However, laser inactivation was demonstrated for the conjugate binding sites.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 23-29 |
| Number of pages | 7 |
| Journal | Proceedings of SPIE - The International Society for Optical Engineering |
| Volume | 1428 |
| State | Published - 1991 |
| Event | Proceedings of Three-Dimensional Bioimaging Systems and Lasers in the Neurosciences - Los Angeles, CA, USA Duration: Jan 23 1991 → Jan 24 1991 |
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Condensed Matter Physics
- Computer Science Applications
- Applied Mathematics
- Electrical and Electronic Engineering