Physical and psychosocial development following liver transplantation

The primary goal of solid organ transplantation is to reverse the consequences of end-stage organ failure and prolong life. Over the past decade, marked advancements have been made in organ preservation, operative techniques, immunosuppression and prevention of infection. One-and 10-year survival rates for paediatric liver transplant (LT) recipients approach 90% and 80%, respectively [1]. Given prolonged life expectancy, posttransplant growth and psychosocial outcomes, including cognitive development, school function and quality of life, have become important secondary goals. Most children with organ failure have some degree of growth failure and developmental delay before transplantation.