Physical Determinants of Diastolic Flow

Zoran B. Popović; James D. Thomas

doi:10.1016/B978-0-323-64067-1.00005-X

Physical Determinants of Diastolic Flow

Zoran B. Popović, James D. Thomas

Medicine, Cardiology Division

Research output: Chapter in Book/Report/Conference proceeding › Chapter

Abstract

The major function of the heart in diastole is to let the blood column flow from the antechambers into the main chambers, while keeping filling pressures to a minimum. During exercise, this task is compounded by shortening of time allowed for filling and increase of volume needed to enter into the cardiac chambers. The three major parameters that define diastole are chamber stiffness, relaxation, and early diastolic suction. We describe the physical determinants of these parameters.

Original language	English (US)
Title of host publication	Diastology
Subtitle of host publication	Clinical Approach to Heart Failure with Preserved Ejection Fraction
Publisher	Elsevier
Pages	53-70
Number of pages	18
ISBN (Electronic)	9780323640671
DOIs	https://doi.org/10.1016/B978-0-323-64067-1.00005-X
State	Published - Jan 1 2020

Keywords

Computer modeling
Diastolic function
Intraventricular pressure gradient
Left ventricular stiffness
Relaxation
Vorticeal flow

ASJC Scopus subject areas

General Medicine

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10.1016/B978-0-323-64067-1.00005-X

Cite this

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AB - The major function of the heart in diastole is to let the blood column flow from the antechambers into the main chambers, while keeping filling pressures to a minimum. During exercise, this task is compounded by shortening of time allowed for filling and increase of volume needed to enter into the cardiac chambers. The three major parameters that define diastole are chamber stiffness, relaxation, and early diastolic suction. We describe the physical determinants of these parameters.

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KW - Relaxation

KW - Vorticeal flow

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Physical Determinants of Diastolic Flow

Abstract

Keywords

ASJC Scopus subject areas

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