Physics and Biology (of Chromosomes)

Research output: Contribution to journalArticle

Abstract

Advances in molecular biology, optics, genetics, and bioinformatics have opened the door to mapping, in molecular detail, processes inside living cells. With the ability to observe the individual moving parts of cellular machinery, concepts formerly confined to physics are entering mainstream biology. This article discusses a few ideas of this sort related to chromosome biology, to illustrate what kinds of insights physics might yet bring to our understanding of living systems.

Original languageEnglish (US)
Pages (from-to)621-631
Number of pages11
JournalJournal of Molecular Biology
Volume432
Issue number2
DOIs
StatePublished - Jan 17 2020

Keywords

  • chromatin
  • chromosomes
  • phase separation
  • polymer biophysics
  • quantitative biology

ASJC Scopus subject areas

  • Structural Biology
  • Molecular Biology

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