Pinealectomy and lesions of the suprachiasmatic nucleus affect the castration response in hamsters exposed to short photoperiods

F. W. Turek, S. H. Losee Olson, G. B. Ellis

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Castration of male hamsters that have been exposed to a nonstimulatory photoperiod (e.g., LD 6:18) results in an attenuated increase in serum LH and FSH levels when compared to the increase observed following castration of hamsters exposed to a stimulatory photoperiod (e.g., LD 14:10). The short-day-induced inhibition of pituitary gonadotrophin release, which is not dependent on the negative feedback effects of gonadal steroid hormones, is abolished if (1) the animals are transferred to LD 14:10; (2) the suprachiasmatic nuclei are lesioned at the time of castration; or (3) pinalectomy accompanies castration. These results indicate that both the pineal gland and the SCN mediate the steroid-independent inhibition of pituitary gonadotropin release that occurs during exposure to short days.

Original languageEnglish (US)
Pages (from-to)335-339
Number of pages5
JournalNeuroendocrinology
Volume36
Issue number5
DOIs
StatePublished - 1983

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology
  • Endocrine and Autonomic Systems
  • Cellular and Molecular Neuroscience

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