Plaques

S. T. Abedon*, E. Bartom

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

1 Scopus citations

Abstract

Plaques are parasite-mediated regions of clearing in especially two-dimensional arrays of target cells. They are important for parasite isolation, enumeration, and characterization, particularly, of virus and bacteriophages. A related procedure, called spotting, is not 100% equivalent to plaquing since spots can form without parasite replication. Various efforts have been made to mathematically model plaque formation, in many cases treating the course of plaque formation as a reaction-diffusion process. This article describes what plaques are, how they form, and complications associated with their use as a means of especially bacteriophage visualization.

Original languageEnglish (US)
Title of host publicationBrenner's Encyclopedia of Genetics
Subtitle of host publicationSecond Edition
PublisherElsevier Inc
Pages356-357
Number of pages2
ISBN (Electronic)9780080961569
ISBN (Print)9780123749840
DOIs
StatePublished - Feb 27 2013

Keywords

  • Bacteriophage
  • Efficiency of center of infection
  • Efficiency of plating
  • Infective center
  • Plaques
  • Reaction-diffusion
  • Virus

ASJC Scopus subject areas

  • Agricultural and Biological Sciences(all)
  • Biochemistry, Genetics and Molecular Biology(all)
  • Medicine(all)

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  • Cite this

    Abedon, S. T., & Bartom, E. (2013). Plaques. In Brenner's Encyclopedia of Genetics: Second Edition (pp. 356-357). Elsevier Inc. https://doi.org/10.1016/B978-0-12-374984-0.01171-2