Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

Philip S. Holzman; Herbert Y. Meltzer; Einar Kringlen; Deborah L. Levy; Shelby J. Haberman; John M. Davis

doi:10.1016/0022-3956(79)90023-2

Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

Philip S. Holzman^*, Herbert Y. Meltzer, Einar Kringlen, Deborah L. Levy, Shelby J. Haberman, John M. Davis

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

Plasma creatine phosphokinase (CPK) activity was determined in single samples of 9 monozygotic and 14 dizygotic twin pairs chosen from an earlier study on the basis of their having been discordant for clinical schizophrenia. The correlations within the MZ pairs was 0.89, and within the DZ pairs was 0.40. The results support a conclusion of genetic control of plasma CPK activity. The mean levels of activity were not abnormal, however.

Original language	English (US)
Pages (from-to)	127-131
Number of pages	5
Journal	Journal of Psychiatric Research
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/0022-3956(79)90023-2
State	Published - Jan 1 1979

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

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AU - Haberman, Shelby J.

AU - Davis, John M.

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