Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

Philip S. Holzman; Herbert Y. Meltzer; Einar Kringlen; Deborah L. Levy; Shelby J. Haberman; John M. Davis

doi:10.1016/0022-3956(79)90023-2

Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

Philip S. Holzman^*, Herbert Y. Meltzer, Einar Kringlen, Deborah L. Levy, Shelby J. Haberman, John M. Davis

^*Corresponding author for this work

Psychiatry and Behavioral Sciences

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Plasma creatine phosphokinase (CPK) activity was determined in single samples of 9 monozygotic and 14 dizygotic twin pairs chosen from an earlier study on the basis of their having been discordant for clinical schizophrenia. The correlations within the MZ pairs was 0.89, and within the DZ pairs was 0.40. The results support a conclusion of genetic control of plasma CPK activity. The mean levels of activity were not abnormal, however.

Original language	English (US)
Pages (from-to)	127-131
Number of pages	5
Journal	Journal of Psychiatric Research
Volume	15
Issue number	2
DOIs	https://doi.org/10.1016/0022-3956(79)90023-2
State	Published - Jan 1 1979

ASJC Scopus subject areas

Psychiatry and Mental health
Biological Psychiatry

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1016/0022-3956(79)90023-2

Cite this

@article{00a2d7d7caa842b69f0a7681e84fe521,

title = "Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia",

abstract = "Plasma creatine phosphokinase (CPK) activity was determined in single samples of 9 monozygotic and 14 dizygotic twin pairs chosen from an earlier study on the basis of their having been discordant for clinical schizophrenia. The correlations within the MZ pairs was 0.89, and within the DZ pairs was 0.40. The results support a conclusion of genetic control of plasma CPK activity. The mean levels of activity were not abnormal, however.",

author = "Holzman, {Philip S.} and Meltzer, {Herbert Y.} and Einar Kringlen and Levy, {Deborah L.} and Haberman, {Shelby J.} and Davis, {John M.}",

year = "1979",

month = jan,

day = "1",

doi = "10.1016/0022-3956(79)90023-2",

language = "English (US)",

volume = "15",

pages = "127--131",

journal = "Journal of Psychiatric Research",

issn = "0022-3956",

publisher = "Elsevier Limited",

number = "2",

}

TY - JOUR

T1 - Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

AU - Holzman, Philip S.

AU - Meltzer, Herbert Y.

AU - Kringlen, Einar

AU - Levy, Deborah L.

AU - Haberman, Shelby J.

AU - Davis, John M.

PY - 1979/1/1

Y1 - 1979/1/1

N2 - Plasma creatine phosphokinase (CPK) activity was determined in single samples of 9 monozygotic and 14 dizygotic twin pairs chosen from an earlier study on the basis of their having been discordant for clinical schizophrenia. The correlations within the MZ pairs was 0.89, and within the DZ pairs was 0.40. The results support a conclusion of genetic control of plasma CPK activity. The mean levels of activity were not abnormal, however.

AB - Plasma creatine phosphokinase (CPK) activity was determined in single samples of 9 monozygotic and 14 dizygotic twin pairs chosen from an earlier study on the basis of their having been discordant for clinical schizophrenia. The correlations within the MZ pairs was 0.89, and within the DZ pairs was 0.40. The results support a conclusion of genetic control of plasma CPK activity. The mean levels of activity were not abnormal, however.

UR - http://www.scopus.com/inward/record.url?scp=0018736302&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0018736302&partnerID=8YFLogxK

U2 - 10.1016/0022-3956(79)90023-2

DO - 10.1016/0022-3956(79)90023-2

M3 - Article

C2 - 573792

AN - SCOPUS:0018736302

VL - 15

SP - 127

EP - 131

JO - Journal of Psychiatric Research

JF - Journal of Psychiatric Research

SN - 0022-3956

IS - 2

ER -

Plasma CPK levels in monozygotic and dizygotic twins discordant for schizophrenia

Abstract

ASJC Scopus subject areas

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this