Plasma lipids and stroke

Philip B. Gorelick*, Theodore Mazzone

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

27 Scopus citations


High plasma levels of lipids are an important modifiable risk factor for coronary heart disease, but are not established as a risk factor for stroke. Pathophysiologic evidence that links lipids to major systemic artery disease, and the results of clinical trials of coronary heart disease prevention in relation to lipid-lowering suggest that lipids may play an important role in the causation of stroke. We discuss the controversy concerning plasma lipids as a risk factor for stroke. A clinical trial targeted at lowering levels of lipids with the aim of primary stroke prevention would be a timely and important contribution. Armed with this information, we could further clarify the plasma lipid-stroke controversy and move into the 21st century with a better understanding of stroke prevention.

Original languageEnglish (US)
Pages (from-to)217-221
Number of pages5
JournalJournal of Cardiovascular Risk
Issue number4
StatePublished - 1999


  • Cholesterol
  • Hyperlipidemia
  • Lipids
  • Stroke

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine


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