Platelets were studied for the presence of antithrombin (thrombin amidolytic inhibitory) activity. Platelet rich plasma contained more antithrombin activity than platelet poor plasma. This activity could be washed from a platelet pellet. Antithrombin activity increased on sonication of platelets but not following aggregation. Platelets contain antithrombin activity connected with the membrane and not involved with the release reaction.
ASJC Scopus subject areas
- Cardiology and Cardiovascular Medicine