Platelet antithrombin activity

Emily E. Czapek; Hau C. Kwaan

doi:10.1016/0049-3848(80)90217-0

Platelet antithrombin activity

Emily E. Czapek^*, Hau C. Kwaan

^*Corresponding author for this work

Medicine, Hematology Oncology Division

Research output: Contribution to journal › Article › peer-review

3 Scopus citations

Abstract

Platelets were studied for the presence of antithrombin (thrombin amidolytic inhibitory) activity. Platelet rich plasma contained more antithrombin activity than platelet poor plasma. This activity could be washed from a platelet pellet. Antithrombin activity increased on sonication of platelets but not following aggregation. Platelets contain antithrombin activity connected with the membrane and not involved with the release reaction.

Original language	English (US)
Pages (from-to)	623-627
Number of pages	5
Journal	Thrombosis Research
Volume	18
Issue number	5
DOIs	https://doi.org/10.1016/0049-3848(80)90217-0
State	Published - Jun 1 1980

Keywords

Platelets
antithrombin-IIJ

ASJC Scopus subject areas

Cardiology and Cardiovascular Medicine
Hematology

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10.1016/0049-3848(80)90217-0

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title = "Platelet antithrombin activity",

abstract = "Platelets were studied for the presence of antithrombin (thrombin amidolytic inhibitory) activity. Platelet rich plasma contained more antithrombin activity than platelet poor plasma. This activity could be washed from a platelet pellet. Antithrombin activity increased on sonication of platelets but not following aggregation. Platelets contain antithrombin activity connected with the membrane and not involved with the release reaction.",

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author = "Czapek, {Emily E.} and Kwaan, {Hau C.}",

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AU - Czapek, Emily E.

AU - Kwaan, Hau C.

PY - 1980/6/1

Y1 - 1980/6/1

N2 - Platelets were studied for the presence of antithrombin (thrombin amidolytic inhibitory) activity. Platelet rich plasma contained more antithrombin activity than platelet poor plasma. This activity could be washed from a platelet pellet. Antithrombin activity increased on sonication of platelets but not following aggregation. Platelets contain antithrombin activity connected with the membrane and not involved with the release reaction.

AB - Platelets were studied for the presence of antithrombin (thrombin amidolytic inhibitory) activity. Platelet rich plasma contained more antithrombin activity than platelet poor plasma. This activity could be washed from a platelet pellet. Antithrombin activity increased on sonication of platelets but not following aggregation. Platelets contain antithrombin activity connected with the membrane and not involved with the release reaction.

KW - Platelets

KW - antithrombin-IIJ

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JF - Thrombosis Research

IS - 5

ER -

Platelet antithrombin activity

Abstract

Keywords

ASJC Scopus subject areas

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