Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

J. A. Oyer; X. Huang; Y. Zheng; J. Shim; T. Ezponda; Z. Carpenter; M. Allegretta; C. I. Okot-Kotber; J. P. Patel; A. Melnick; R. L. Levine; A. Ferrando; A. D. MacKerell; N. L. Kelleher; J. D. Licht; R. Popovic

doi:10.1038/leu.2013.204

Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

J. A. Oyer, X. Huang, Y. Zheng, J. Shim, T. Ezponda, Z. Carpenter, M. Allegretta, C. I. Okot-Kotber, J. P. Patel, A. Melnick, R. L. Levine, A. Ferrando, A. D. MacKerell, N. L. Kelleher, J. D. Licht, R. Popovic

Molecular Biosciences

Research output: Contribution to journal › Letter › peer-review

114 Scopus citations

Original language	English (US)
Pages (from-to)	198-201
Number of pages	4
Journal	Leukemia
Volume	28
Issue number	1
DOIs	https://doi.org/10.1038/leu.2013.204
State	Published - 2014

ASJC Scopus subject areas

Hematology
Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.1038/leu.2013.204

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Oyer, J. A., Huang, X., Zheng, Y., Shim, J., Ezponda, T., Carpenter, Z., Allegretta, M., Okot-Kotber, C. I., Patel, J. P., Melnick, A., Levine, R. L., Ferrando, A., MacKerell, A. D., Kelleher, N. L., Licht, J. D., & Popovic, R. (2014). Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies. Leukemia, 28(1), 198-201. https://doi.org/10.1038/leu.2013.204

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title = "Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies",

author = "Oyer, {J. A.} and X. Huang and Y. Zheng and J. Shim and T. Ezponda and Z. Carpenter and M. Allegretta and Okot-Kotber, {C. I.} and Patel, {J. P.} and A. Melnick and Levine, {R. L.} and A. Ferrando and MacKerell, {A. D.} and Kelleher, {N. L.} and Licht, {J. D.} and R. Popovic",

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Oyer, JA, Huang, X, Zheng, Y, Shim, J, Ezponda, T, Carpenter, Z, Allegretta, M, Okot-Kotber, CI, Patel, JP, Melnick, A, Levine, RL, Ferrando, A, MacKerell, AD, Kelleher, NL, Licht, JD & Popovic, R 2014, 'Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies', Leukemia, vol. 28, no. 1, pp. 198-201. https://doi.org/10.1038/leu.2013.204

TY - JOUR

T1 - Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

AU - Oyer, J. A.

AU - Huang, X.

AU - Zheng, Y.

AU - Shim, J.

AU - Ezponda, T.

AU - Carpenter, Z.

AU - Allegretta, M.

AU - Okot-Kotber, C. I.

AU - Patel, J. P.

AU - Melnick, A.

AU - Levine, R. L.

AU - Ferrando, A.

AU - MacKerell, A. D.

AU - Kelleher, N. L.

AU - Licht, J. D.

AU - Popovic, R.

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SN - 0887-6924

VL - 28

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Point mutation E1099K in MMSET/NSD2 enhances its methyltranferase activity and leads to altered global chromatin methylation in lymphoid malignancies

ASJC Scopus subject areas

UN SDGs

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