@article{080069a682a240628f1abda0acd975f2,
title = "Point-of-Care Technology Research Network: An evolving model for collaborative translational research in biomedical engineering",
abstract = "As the healthcare system evolves from a centralized, hospital- and office-based model to an emphasis on patient-centric care delivered in decentralized settings from the community and/or home to low resource settings domestically and internationally, some Point-of-Care Technologies (POCT) have become important and others may soon become important in facilitating care. These portable diagnostic and monitoring devices enable moving care closer to the patient. We review recent developments in a national model to accelerate the development of POCT, specifically the Point-of-Care Technology Research Network (POCTRN), comprising a multi-center scientific network supported by a coordinating center. We summarize the history of the Network, and then describe the primary objectives and key activities of the Network and highlight the role of a new coordinating center providing administrative and infrastructure support. POCTRN is committed to building evidence-based best practices for high-quality translation and commercialization in biomedical engineering to maximize clinical impact of Point-of-Care Technologies.",
keywords = "Collaboration, Innovation, Network, Point-of-Care, Technology, Translational research",
author = "Carleton, {Penny Ford} and Steve Schachter and Lash, {Tiffani Bailey} and Jue Chen and Todd Merchak and Oliver Brand and Bryan Buchholz and Charlotte Gaydos and Wilbur Lam and Yukari Manabe and Greg Martin and Sally McFall and David McManus and Robert Murphy and John Parrish",
note = "Funding Information: POCTRN is committed to building evidence-based best practices for high-quality translation and commercialization to maximize clinical impact of POC technologies. From 2012 to 2017, POCTRN supported over 90 projects and provided consultation and engagement with ∼2500 other researchers. Comprehensive metrics for the entire network will be reported in a separate publication. As an example of the impact that an individual Center can have, the Point-of-Care Technology Research Center in Primary Care achieved the following metrics from 2012 to 2017: • Created a portfolio of 31 awards at different levels of maturity across the development pipeline with >65% still active in Year 5 • Established a national award network (e.g., 66% of projects funded in Year 4 and 5 were from outside the regional base of the Center) • Increasing emphasis towards the end of the 5-year period on funding companies to support later stage development with increased likelihood of near-term impact (e.g., 50% of awards in Year 5) • Enabled funding: $48.5 million (approximately 20X the NIBIB investment) • Publications: 43 (37 scientific, 6 Center leadership) • Patents: 8 (2 issued, 4 full applications; 2 provisional applications) • Presentations: 57 conference proceedings and presentations. Funding Information: Appropriate funding sources need to be acknowledged, including all theU54 Center grants, and the grants to the coordinating center. Additional support for DDM was provided by NIH grants U54HL143541 , R01HL126911 , R01HL126911 , R01HL137734 , R01HL137794 , R01HL135219 , R01HL141434 , and National Science Foundation grant NSF-12-512 . DDM has received research support from Apple , Bristol-Myers Squibb , Flexcon , Samsung , Pfizer , Philips , Biotronik , and Boehringer Ingelheim . DDM has received consulting fees or honoraria from Bristol Myers Squibb , Pfizer , Samsung Electronics , and FlexCon . C-THAN is “supported by the National Institute of Biomedical Imaging and Bioengineering , Fogarty International Center and the Office of AIDS Research of the National Institutes of Health under Award Number U54EB027049 . The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.” ",
year = "2019",
month = sep,
doi = "10.1016/j.cobme.2019.10.011",
language = "English (US)",
volume = "11",
pages = "145--148",
journal = "Current Opinion in Biomedical Engineering",
issn = "2468-4511",
publisher = "Elsevier BV",
}