Polymer-caged lipsomes: A pH-responsive delivery system with high stability

Sang Min Lee, Haimei Chen, Christine M. Dettmer, Thomas V. O'Halloran*, Sonbinh T. Nguyen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

187 Scopus citations


Polymer-incorporated liposomes were prepared from preformed liposomes and a cholesterol-functionalized poly(acrylic acid) additive via a simple drop-in procedure. These modified liposomes possess surface-active carboxylate groups that can be cross-linked with telechelic 2,2′-(ethylenedioxy)bis(ethylamine) linkers, resulting in polymer-caged liposomes (PCLs) that are highly stable and have tunable pH-sensitive responses.

Original languageEnglish (US)
Pages (from-to)15096-15097
Number of pages2
JournalJournal of the American Chemical Society
Issue number49
StatePublished - Dec 12 2007

ASJC Scopus subject areas

  • Catalysis
  • Chemistry(all)
  • Biochemistry
  • Colloid and Surface Chemistry

Fingerprint Dive into the research topics of 'Polymer-caged lipsomes: A pH-responsive delivery system with high stability'. Together they form a unique fingerprint.

Cite this