Polymers and proteins: Interactions at interfaces

Igal Szleifer*

*Corresponding author for this work

Research output: Contribution to journalArticle

166 Scopus citations

Abstract

The ability of polymer molecules attached at one end to a surface to prevent or enhance protein adsorption has been studied experimentally and theoretically. Recent systematic studies show that surface density seems to be the most important property of the tethered layer that determines its ability to prevent protein adsorption. Theoretical studies predict that the interactions of the polymer layer with the proteins and the adsorption behavior do not depend in the same way on polymer molecular weight and on the type of interaction of the polymer with the surface.

Original languageEnglish (US)
Pages (from-to)337-344
Number of pages8
JournalCurrent Opinion in Solid State and Materials Science
Volume2
Issue number3
DOIs
StatePublished - Jan 1 1997

Keywords

  • EO ethylene oxide
  • PEG polyethylene glycol
  • PEO polyethylene oxide
  • PS polystyrene
  • SCMF single-chain mean-field

ASJC Scopus subject areas

  • Materials Science(all)

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