Population-Wide Sodium Reduction: The Bumpy Road from Evidence to Policy

Lawrence J. Appel*, Sonia Y. Angell, Laura K. Cobb, Heather M. Limper, David E. Nelson, Jonathan M. Samet, Ross C. Brownson

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

39 Scopus citations


Elevated blood pressure is a highly prevalent condition that is etiologically related to coronary heart disease and stroke, two of the leading causes of morbidity and mortality throughout the world. Excess salt (sodium chloride) intake is a major determinant of elevated blood pressure. In this article, we discuss the scientific rationale for population-wide salt reduction, the types and strength of available evidence, policy-making on dietary salt intake in the United States and other countries, and the role and impact of key stakeholders. We highlight a number of lessons learned, many of which are germane to policy development in other domains.

Original languageEnglish (US)
Pages (from-to)417-425
Number of pages9
JournalAnnals of Epidemiology
Issue number6
StatePublished - Jun 2012


  • Blood Pressure
  • Cardiovascular Disease
  • Hypertension
  • Nutrition
  • Policy
  • Salt
  • Sodium

ASJC Scopus subject areas

  • Epidemiology


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