Portable real-time photoacoustic microscopy

Konstantin Maslov*, Hao F. Zhang, Lihong V. Wang

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingConference contribution

7 Scopus citations

Abstract

To make a photoacoustic microscope (PAM) suitable for clinical applications, we have developed a portable PAM system with high frame rate. The probe for this portable PAM system is a small hand-held unit, which is connected with the rest of the system with an optical fiber and electrical cables. The probe can be maneuvered easily and pressed against the region of interest at various anatomical sites. By employing a tunable laser with a repetition rate up to 1 kHz, this portable PAM system has reduced its acquisition time to less than one second for each cross-sectional image. We have applied this system to animals as well as humans to acquire cross-sectional images with a maximum imaging depth of 5 mm, a lateral resolution of better than 100 μm, and an axial resolution of 35 μm.

Original languageEnglish (US)
Title of host publicationPhotons Plus Ultrasound
Subtitle of host publicationImaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
DOIs
StatePublished - 2007
EventPhotons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics - San Jose, CA, United States
Duration: Jan 21 2007Jan 24 2007

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume6437
ISSN (Print)1605-7422

Other

OtherPhotons Plus Ultrasound: Imaging and Sensing 2007: The Eighth Conference on Biomedical Thermoacoustics, Optoacoustics, and Acousto-optics
CountryUnited States
CitySan Jose, CA
Period1/21/071/24/07

Keywords

  • Functional imaging
  • Medical and biological imaging
  • Photoacoustic imaging
  • Photoacoustic microscopy

ASJC Scopus subject areas

  • Electronic, Optical and Magnetic Materials
  • Biomaterials
  • Atomic and Molecular Physics, and Optics
  • Radiology Nuclear Medicine and imaging

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