Possible case of CNS Whipple's disease in an adolescent with AIDS

Sameer J. Patel*, Richard C. Huard, Christian Keller, Marc Foca

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


An adolescent with HIV/AIDS presented subacutely with progressive encephalopathy, spastic quadraplegia, and diarrhea. His brain biopsy was suggestive of central nervous system Whipple's disease, a disease rarely described in HIV patients. Due to overlapping, nonspecific symptoms associated with several opportunistic infections and to the difficulty in culturing the causative organism Tropheryma whipplei, Whipple's disease may be more common than previously suspected, and it is an important consideration in patients with AIDS.

Original languageEnglish (US)
Pages (from-to)69-73
Number of pages5
JournalJournal of the International Association of Physicians in AIDS Care
Issue number2
StatePublished - Mar 2008


  • AIDS
  • HIV
  • Whipple's disease
  • encephalopathy

ASJC Scopus subject areas

  • Immunology
  • Dermatology
  • Infectious Diseases


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