Posterior petrous face meningiomas presenting with Ménière's-like syndrome: a case series and review of the literature

Ramin A. Morshed, Nicole T. Jiam, Elaina J. Wang, Stephen T. Magill, Renata M. Knoll, Elliott D. Kozin, Philip V. Theodosopoulos, Steven W. Cheung, Jeffrey D. Sharon, Michael W. McDermott*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

Abstract

OBJECTIVE Ménière's disease is an inner ear disorder classically characterized by fluctuating hearing loss, tinnitus, and aural fullness accompanied by episodic vertigo. While the pathogenesis of Ménière's remains under debate, histopathological analyses implicate endolymphatic sac dysfunction with inner ear fluid homeostatic dysregulation. Little is known about whether external impingement of the endolymphatic sac by tumors may present with Ménière's-like symptoms. The authors present a case series of 7 patients with posterior fossa meningiomas that involved the endolymphatic sac and new onset of Ménière's-like symptoms and review the literature on this rare clinical entity. METHODS A retrospective review of patients undergoing resection of a posterior petrous meningioma was performed at the authors' institution. Inclusion criteria were age older than 18 years; patients presenting with Ménière's-like symptoms, including episodic vertigo, aural fullness, tinnitus, and/or hearing loss; and tumor location overlying the endolymphatic sac. RESULTS There were 7 cases of posterior petrous face meningiomas involving the vestibular aperture presenting with Ménière's-like symptoms. Imaging and intraoperative examination confirmed no cranial nerve VIII compression or labyrinthine artery involvement accounting for audiovestibular symptoms. Of the 7 patients in the series, 6 experienced significant improvement or resolution of their vertigo, and all 7 had improvement or resolution of their tinnitus after resection. Of the 5 patients who had preoperative hearing loss, 2 experienced improvement or resolution of their ipsilateral preoperative hearing deficit, whereas the other 3 had unchanged hearing loss compared to preoperative evaluation. CONCLUSIONS Petrous face meningiomas overlying the endolymphatic sac can present with a Ménière's syndrome. Early recognition and microsurgical excision of these tumors is critical for resolution of most symptoms and stabilization of hearing loss.

Original languageEnglish (US)
Pages (from-to)441-448
Number of pages8
JournalJournal of neurosurgery
Volume136
Issue number2
DOIs
StatePublished - Feb 2022
Externally publishedYes

Keywords

  • Ménière's syndrome
  • endolymphatic sac
  • meningioma
  • posterior petrous
  • skull base

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

Fingerprint

Dive into the research topics of 'Posterior petrous face meningiomas presenting with Ménière's-like syndrome: a case series and review of the literature'. Together they form a unique fingerprint.

Cite this