Postoperative management of ulcerative colitis and Crohn's disease

Rajesh N. Keswani, Russell D. Cohen*

*Corresponding author for this work

Research output: Contribution to journalReview articlepeer-review

5 Scopus citations

Abstract

Approximately 10% to 30% of patients with ulcerative colitis and up to 70% of patients with Crohn's disease will undergo surgery at some point during their lifetime. Although patients with ulcerative colitis are considered "cured" by surgery, patients who have undergone an ileal pouch anal anastomosis may develop pouchitis, cuffitis, pouch irritability, or even Crohn's disease. Various therapies have shown success, including probiotics, in the prevention of pouchitis onset or relapse. Crohn's disease historically recurs following surgery; prophylaxis against disease recurrence has been attempted with a variety of agents, with variable success. Innovative therapies holding promise for the future treatment or prevention of these conditions are under exploration.

Original languageEnglish (US)
Pages (from-to)492-499
Number of pages8
JournalCurrent gastroenterology reports
Volume7
Issue number6
DOIs
StatePublished - Dec 2005

ASJC Scopus subject areas

  • Gastroenterology

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