Postpartum glucose tolerance in women with gestational diabetes using levonorgestrel intrauterine contraception

Jessica W. Kiley*, Cassing Hammond, Charlotte Niznik, Alfred Rademaker, Dachao Liu, Lee P. Shulman

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

Objective: Postpartum contraception is critical in women with gestational diabetes mellitus (GDM). We evaluated the effect of the levonorgestrel intrauterine system (LNG-IUS) on glucose tolerance in postpartum women with GDM. Study design: The study is a descriptive analysis of 12-month glucose tolerance in women with recent GDM who used the LNG-IUS, the copper IUD or postpartum sterilization. Results: Twelve months postpartum, 3 of 13 LNG-IUS users (23.1%) and 1 of 6 nonhormonal contraceptive users (16.6%) had prediabetes. No woman developed overt diabetes. Conclusions: This study is the first and only to measure the metabolic effects of the LNG-IUS women with GDM. Larger trials are necessary. Implications: Use of levonorgestrel intrauterine contraception does not appear to negatively affect glucose tolerance in postpartum women with a history of gestational diabetes. Additional appropriately powered clinical studies are needed to confirm these results.

Original languageEnglish (US)
Pages (from-to)67-70
Number of pages4
JournalContraception
Volume91
Issue number1
DOIs
StatePublished - Jan 1 2015

Keywords

  • Gestational diabetes
  • Glucose tolerance
  • Intrauterine device
  • LARC
  • Postpartum contraception

ASJC Scopus subject areas

  • Reproductive Medicine
  • Obstetrics and Gynecology

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