Postpartum hemorrhage: Evidence-based medical interventions for prevention and treatment

Priya V. Rajan, Deborah A. Wing

Research output: Contribution to journalReview articlepeer-review

47 Scopus citations

Abstract

Postpartum hemorrhage (PPH) remains a significant contributor to maternal morbidity and mortality throughout the world. The majority of research on this topic has focused on efforts to prevent PPH. Sound data exist that active management of the third stage of labor can reduce the occurrence of PPH. Although there remains debate regarding the optimal protocol for active management, it appears at this time that oxytocin is the preferable uterotonic to use. Misoprostol may be a reasonable option where parenteral administration of an uterotonic is not feasible. There is little evidence to guide treatment decisions should PPH occur.

Original languageEnglish (US)
Pages (from-to)165-181
Number of pages17
JournalClinical Obstetrics and Gynecology
Volume53
Issue number1
DOIs
StatePublished - Mar 1 2010

Keywords

  • Ergot alkaloids
  • Misoprostol
  • Oxytocin
  • Postpartum hemorrhage
  • Third stage of labor
  • Uterotonic

ASJC Scopus subject areas

  • Obstetrics and Gynecology

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