TY - JOUR
T1 - Postpartum hemorrhage revisited
T2 - New challenges and solutions
AU - Higgins, Nicole
AU - Patel, Samir Kaushik
AU - Toledo, Paloma
N1 - Funding Information:
P.T. is currently supported by research grants from the National Institute on Minority Health and Health Disparities (R03MD011628-01) and the Agency for Healthcare Research and Quality (R03HS025267-01). The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institute on Minority Health and Health Disparities or the Agency for Healthcare Research and Quality.
Publisher Copyright:
© 2019 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2019
Y1 - 2019
N2 - Purpose of reviewPostpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality in the United States, and worldwide. Recognition of PPH is challenging, but once hemorrhage is recognized, management needs to focus on achieving adequate uterine tone and maintaining maternal hemodynamic stability. There have been several advances in the management of postpartum hemorrhage, many of which can be implemented at the labor and delivery unit level.Recent findingsThere have been many advances in the understanding of at-risk parturients, and the use of hemorrhage protocols and safety bundles have been shown to improve patient outcomes. There are many new advances in transfusion management (e.g. fibrinogen concentrate, prothrombin complex concentrate, tranexamic acid) that can compliment traditional component therapy. Consideration should be given to transferring women at high risk for complications (e.g. invasive placentation) to a higher level facility for delivery.SummaryAlthough postpartum hemorrhage itself may not be preventable, early identification of blood loss, and mobilization of resources may prevent adverse outcomes. Multidisciplinary planning at the system level, ensuring that hemorrhage protocols exist, as well as for management of high-risk patients is important for improving patient outcomes.
AB - Purpose of reviewPostpartum hemorrhage (PPH) is a leading cause of maternal morbidity and mortality in the United States, and worldwide. Recognition of PPH is challenging, but once hemorrhage is recognized, management needs to focus on achieving adequate uterine tone and maintaining maternal hemodynamic stability. There have been several advances in the management of postpartum hemorrhage, many of which can be implemented at the labor and delivery unit level.Recent findingsThere have been many advances in the understanding of at-risk parturients, and the use of hemorrhage protocols and safety bundles have been shown to improve patient outcomes. There are many new advances in transfusion management (e.g. fibrinogen concentrate, prothrombin complex concentrate, tranexamic acid) that can compliment traditional component therapy. Consideration should be given to transferring women at high risk for complications (e.g. invasive placentation) to a higher level facility for delivery.SummaryAlthough postpartum hemorrhage itself may not be preventable, early identification of blood loss, and mobilization of resources may prevent adverse outcomes. Multidisciplinary planning at the system level, ensuring that hemorrhage protocols exist, as well as for management of high-risk patients is important for improving patient outcomes.
KW - cell salvage
KW - hemorrhage protocols
KW - postpartum hemorrhage
KW - risk stratification
KW - transfusion strategies
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U2 - 10.1097/ACO.0000000000000717
DO - 10.1097/ACO.0000000000000717
M3 - Article
C2 - 31045634
AN - SCOPUS:85065543037
SN - 0952-7907
VL - 32
SP - 278
EP - 284
JO - Current opinion in anaesthesiology
JF - Current opinion in anaesthesiology
IS - 3
ER -