Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Victoria A. Mancuso; Thomas J. Hope; Li Zhu; David Derse; Tom Phillips; Tristram G. Parslow

doi:10.1128/jvi.68.3.1998-2001.1994

Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Victoria A. Mancuso, Thomas J. Hope, Li Zhu, David Derse, Tom Phillips, Tristram G. Parslow^*

^*Corresponding author for this work

Cell & Developmental Biology

Research output: Contribution to journal › Comment/debate › peer-review

53 Scopus citations

Abstract

By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

Original language	English (US)
Pages (from-to)	1998-2001
Number of pages	4
Journal	Journal of virology
Volume	68
Issue number	3
DOIs	https://doi.org/10.1128/jvi.68.3.1998-2001.1994
State	Published - Mar 1994

ASJC Scopus subject areas

Insect Science
Virology
Microbiology
Immunology

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10.1128/jvi.68.3.1998-2001.1994

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abstract = "By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.",

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T1 - Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

AU - Mancuso, Victoria A.

AU - Hope, Thomas J.

AU - Zhu, Li

AU - Derse, David

AU - Phillips, Tom

AU - Parslow, Tristram G.

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N2 - By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

AB - By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

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DO - 10.1128/jvi.68.3.1998-2001.1994

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JO - Journal of virology

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Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Abstract

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