Posttranscriptional effector domains in the Rev proteins of feline immunodeficiency virus and equine infectious anemia virus

Victoria A. Mancuso, Thomas J. Hope, Li Zhu, David Derse, Tom Phillips, Tristram G. Parslow*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

52 Scopus citations

Abstract

By systematically dissecting the Rev proteins of feline immunodeficiency virus (FIV) and equine infectious anemia virus (EIAV), we have identified within each a short peptide that is functionally interchangeable with the effector domains found in Rev-like proteins from other retroviruses. The active sequences from FIV and EIAV differ in several respects from other known effectors and may represent a distinct class of effector domain.

Original languageEnglish (US)
Pages (from-to)1998-2001
Number of pages4
JournalJournal of virology
Volume68
Issue number3
DOIs
StatePublished - Mar 1994

ASJC Scopus subject areas

  • Microbiology
  • Immunology
  • Insect Science
  • Virology

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