Posttransplant Heart Failure

Philip T. Thrush*, Simon Urschel, Elfriede Pahl

*Corresponding author for this work

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Orthotopic heart transplantation (HT) is an option for end-stage heart failure in pediatric patients with a variety of diagnoses. However, posttransplant survival is limited by graft failure, which can occur at any point in time following transplantation. This chapter provides a comprehensive overview of the causes of graft failure in pediatric HT, as well as highlighting pathophysiology, evaluation, and management strategies.

Original languageEnglish (US)
Title of host publicationHeart Failure in the Child and Young Adult
Subtitle of host publicationFrom Bench to Bedside
PublisherElsevier
Pages625-638
Number of pages14
ISBN (Electronic)9780128026137
ISBN (Print)9780128023938
DOIs
StatePublished - Jan 1 2018

Keywords

  • Acute cellular rejection
  • Allograft vasculopathy
  • Antibody-mediated rejection
  • Graft failure
  • Pediatric heart transplantation

ASJC Scopus subject areas

  • Medicine(all)

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  • Cite this

    Thrush, P. T., Urschel, S., & Pahl, E. (2018). Posttransplant Heart Failure. In Heart Failure in the Child and Young Adult: From Bench to Bedside (pp. 625-638). Elsevier. https://doi.org/10.1016/B978-0-12-802393-8.00047-8