Postural Stability as a Measure of Fall Risk in Older People with and without HIV

Mary Clare Masters, Laura M. Campbell, Jimmy Yu, Anne Heaton, Kristine M. Erlandson, Hari Garudadri, Truong Nguyen, David J. Moore, Raeanne C. Moore*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

As the number of older people with HIV (PWH) grows, accidental falls and their associated negative health outcomes are of increasing concern. Fall risk can be measured using novel screening tools such as evaluating postural stability using force plate technology. The aims of this study were to test this technology to assess fall risk among older PWH. In a cross-sectional, observational study of people without HIV (PWoH) with a range of fall risk, participants underwent balance assessment using the validated BTrackS balance plate. Postural stability was compared by HIV serostatus. Multivariable linear regressions were used to examine the relationship between postural stability and validated measures of fall risk balance and frailty status. Among 34 PWH and 30 PWoH, all ‡50 years, postural stability was worse among PWH (35.4 cm vs. 28.3 cm, p = .07). In multivariable models, worse postural stability was associated with reporting a fall in the past 6 months (b = 0.32, p = .004), worse fall efficacy (b = 0.45, p < .001), and being frail or prefrail (b = 0.26, p = .027). In multivariable models stratified by HIV serostatus, worse postural stability was significantly associated with worse fall efficacy (b = 0.53, p < .01) and lower balance confidence (b = -0.33, p =. 04) among PWH but not PWoH. Among older PWH and PWoH, worse postural stability was associated with validated measures of fall risk, including history of falls and poorer fall efficacy. Assessment of postural sway is a promising objective screening test for fall risk among older PWH.

Original languageEnglish (US)
JournalAIDS research and human retroviruses
DOIs
StateAccepted/In press - 2024

Funding

This work was supported by the Gilead Sciences Research Scholars Program (R.C.M.). National Institute on Aging (NIA) of the National Institutes of Health under Award Numbers 5R03AG067980 (M.C.M.), K23AG082543 (M.C.M.), K24AG082527 (K.M.E.), R01AG062387 (R.C.M.). This work was further supported by the National Institute of Mental Health (NIMH)-funded Sustained Training in Aging and HIV Research program [STAHR; R25MH108389 ] and the NIMH HIV Neurobehavioral Research Center [HNRC; P30MH062512 ]. The content is solely the responsibility of the authors and does not necessarily represent the official views of the National Institutes of Health.

Keywords

  • aging
  • balance
  • falls
  • HIV-1
  • mobility

ASJC Scopus subject areas

  • Immunology
  • Virology
  • Infectious Diseases

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