POT1 mutation spectrum in tumour types commonly diagnosed among POT1 -associated hereditary cancer syndrome families

Keyphrases

• Tumor Subtype 100%
• Mutation Spectrum 100%
• Hereditary Cancer Syndromes 100%
• Protection of Telomeres 1 100%
• Tumor 25%
• Angiosarcoma 25%
• Germ Cells 18%
• Colorectal Cancer 12%
• Glioma 12%
• Telomere Shortening 12%
• Mutation Frequency 12%
• Shelterin 12%
• Malignant Glioma 6%
• Malignancy 6%
• Next-generation Sequencing 6%
• Melanoma 6%
• Autosomal Dominant 6%
• Genomic Instability 6%
• Gliomagenesis 6%
• Logistic Regression 6%
• Telomere Length 6%
• Chronic Lymphocytic Leukemia 6%
• Sporadic Cancer 6%
• Familial Cancer Syndrome 6%
• Colorectal Melanoma 6%
• Tumor mutational Burden 6%
• Familial Cancer Risk 6%

Medicine and Dentistry

• Neoplasm 100%
• Familial Cancer 100%
• Telomere 100%
• Angiosarcoma 22%
• Germ Cell 16%
• Ganglioglioma 11%
• Colorectal Carcinoma 11%
• Melanoma 11%
• Mutation Rate 11%
• Shelterin 11%
• Cancer 11%
• Logistic Regression Analysis 5%
• Glioblastoma 5%
• Somatics 5%
• Cancer Risk 5%
• Genomic Instability 5%
• Autosomal Dominant Inheritance 5%
• Next Generation Sequencing 5%
• B-Cell Chronic Lymphocytic Leukemia 5%
• Cancer Syndrome 5%
• Telomere Homeostasis 5%

Biochemistry, Genetics and Molecular Biology

• Telomere 100%
• Germline 17%
• Germ Cell 17%
• Mutation Rate 11%
• Shelterin 11%
• Genome Instability 5%
• Next Generation Sequencing 5%
• Autosomal Dominant Inheritance 5%
• Telomere Homeostasis 5%
• Telomere Length 5%