Potential benefits of alkali therapy to prevent GFR loss: Time for a palatable solution for the management of CKD

Vaibhav Sahni, Robert M. Rosa, Daniel Batlle*

*Corresponding author for this work

Research output: Contribution to journalComment/debatepeer-review

8 Scopus citations

Abstract

There is increasing evidence that alkali therapy can retard progression of chronic kidney disease (CKD). We summarize recent studies and discuss a mechanism whereby alkali therapy may neutralize acid production associated with typical Western diets, which generate acid. We emphasize the rationale for using alkali therapy early in the course of CKD, even in the absence of overt metabolic acidosis, and we urge the pharmaceutical industry to develop palatable alkali-containing solutions.

Original languageEnglish (US)
Pages (from-to)1065-1067
Number of pages3
JournalKidney international
Volume78
Issue number11
DOIs
StatePublished - Dec 2010

ASJC Scopus subject areas

  • Nephrology

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