Power estimation predicts specific function action of acupuncture: An fMRI study

Peng Liu, Guangyu Zhou, Xuejuan Yang, Jixin Liu, Jinbo Sun, Minghao Dong, Kai Yuan, Yi Zhang, Wei Qin, Jie Tian*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

8 Scopus citations


Purpose: The purpose was to investigate the distinct pattern of brain response induced by electroacupuncture stimulation (EAS) related to sustained acupuncture effects. Material and Methods: Twenty-eight healthy volunteers were enrolled and randomized into two groups. According to grouping, volunteers were separately treated by EAS at GB37 (Guangming) or KI8 (Jiaoxin) during functional magnetic resonance imaging. Differences in acupuncture effects between the groups were tested by the power estimation approach. Results: Spatial patterns of the whole brain power were different in the periaqueductal gray, occipital cortex (OC) and temporal cortex when induced by EAS at GB37 and KI8. Moreover, the differences in the sustained effects between these two acupoints were also identified and associated with the OC, dorsolateral prefrontal cortex, medial prefrontal cortex, anterior cingulate cortex and insula. Conclusion: Electroacupuncture stimulation induced different power fluctuation patterns related to GB37 and KI8. We suggest that these findings might be attributed to the specific function action of these acupoints.

Original languageEnglish (US)
Pages (from-to)1059-1064
Number of pages6
JournalMagnetic Resonance Imaging
Issue number8
StatePublished - Oct 2011
Externally publishedYes


  • Acupuncture
  • FMRI
  • Power estimation

ASJC Scopus subject areas

  • Biophysics
  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging


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